SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics
ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao +11 more
wiley +1 more source
The mosaic memory of large language models. [PDF]
Shilov I, Meeus M, de Montjoye YA.
europepmc +1 more source
Multi-parameter fuzzy design space for QbD approach applied in the development of biomedical devices
Daniel René Tasé Velázquez +6 more
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The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Optimizing renewable energy investments using artificial intelligence-based multi-facet fuzzy decision models. [PDF]
Dinçer H +3 more
europepmc +1 more source
A causal model of the impact of the “fuzzy front end” on the success of new product development
Cornelius Herstatt, Birgit Verworn
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A smart power‐generating coating is developed to harvest energy from both ambient humidity and impacting liquid droplets. The integrated system delivers sustained open‐circuit voltages of 0.85 V from moisture and up to 36 V from droplets. Its scalable coating architecture enables a continuous power supply for low‐power electronic devices.
Liang Ma +5 more
wiley +1 more source
Generalized FitzHugh-Nagumo equations with Caputo gH-differentiability: A novel fuzzy fractional approach to digital memristor networks. [PDF]
Yousuf M +3 more
europepmc +1 more source
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng +16 more
wiley +1 more source
A Dynamic Hybrid Weighting Framework for Teaching Effectiveness Evaluation in Multi-Criteria Decision-Making: Integrating Interval-Valued Intuitionistic Fuzzy AHP and Entropy Triggering. [PDF]
Lu C, Zhang Y.
europepmc +1 more source

