Results 111 to 120 of about 6,305 (306)

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Mining Fuzzy Multiple-Level Association Rules from Quantitative Data

, 2012
[[abstract]]Machine-learning and data-mining techniques have been developed to turn data into useful task-oriented knowledge. Most algorithms for mining association rules identify relationships among transactions using binary values and find rules at a ...
Lin, Kuei-Ying, Chen, Been-Chian, Hong, Tzung-Pei   +2 more
core  

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

Fuzzy inferencing using single-antecedent fuzzy rules

, 2006
The output of a fuzzy cognitive map (FCM) is the summation of the products of its individual input variables and their relative weights to each node. This additive nature is the main hindrance to the implementation of fuzzy theory in FCM, as conventional
Wong, K.W., Khan, M.S., Khor, S.W.
core  

Creating Personalized Higher Education Teaching System Using Fuzzy Association Rule Mining

International Journal of Computational Intelligence Systems
Universities and colleges aim to provide students with a solid academic foundation. Quality instruction is one strategy for achieving the highest possible standard in the higher education system.
Dezhi Li
doaj   +1 more source

Mining Linguistic Associations for Emergent Flood Prediction Adjustment

Advances in Fuzzy Systems, 2013
Floods belong to the most hazardous natural disasters and their disaster management heavily relies on precise forecasts. These forecasts are provided by physical models based on differential equations. However, these models do depend on unreliable inputs
Michal Burda, Pavel Rusnok, Martin Štěpnička   +2 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Fuzzy rule interpolation for multidimensional input space with petroleum engineering application

, 2001
Fuzzy rule based systems have been very popular in many engineering applications. In petroleum engineering, fuzzy rules are normally constructed using some fuzzy rule extraction techniques to establish the petrophysical property prediction model. However,
Wong, K.W., Gedeon, T.D.
core  

Malware traffic detection based on type II fuzzy recognition

Frontiers in Physics
In recent years, a surge in malicious network incidents and instances of network information theft has taken place, with malware identified as the primary culprit.
Weisha Zhang, Jiajia Liu, Jimin Peng, Qiang Liu, Kun Yu   +4 more
doaj   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source