Results 121 to 130 of about 28,372 (302)

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

State Evaluation of Self-Powered Wireless Sensors Based on a Fuzzy Comprehensive Evaluation Model. [PDF]

Sensors (Basel), 2023
Xiong S, Li Q, Yang A, Zhu L, Li P, Xue K, Yang J.   +6 more
europepmc   +1 more source

Comprehensive Evaluation Model-Based Fuzzy Math of Tailings Dam Stability

, 2010
Aiming at the high occurrence of accident at broken tailing dam and its significance in safety, the defects of evaluation methods currently used were pointed out.
Long Jun Dong, Fei Yue Wang, Zhi Sheng Xu   +2 more
core   +1 more source

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

Advanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi, Minying Low, Peng Xiu, Kresten Lindorff‐Larsen, Yong Wang   +4 more
wiley   +1 more source

Fuzzy comprehensive evaluation and quantitative weight analysis in structure management of human resources. [PDF]

PLoS One, 2023
Zhang H.
europepmc   +1 more source

Research on risk fuzzy comprehensive evaluation for construction engineering projects based on AHM

, 2017
It is necessary for investors and construction enterprises to evaluate project risk objectively in order to manage and control project risk effectively and further reduce economic losses.
He, Chunbao, Gaoyang Li, Michael Packianather, Li, Gaoyang, Chunbao He, Mingguang Liu, Liu, Mingguang, Packianather, Michael   +7 more
core   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

Advanced Science, EarlyView.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen, Jiayi Liang, Yujia Wu, Jianan Xu, Yi Liu, Wenguang Wang, Xinhang Jiang, Benjie Gao, Yueyue Wang, Hui Jiang   +9 more
wiley   +1 more source

Gradation optimization of AC-20 asphalt mixture based on the fuzzy analytic hierarchy process and comprehensive evaluation method

Frontiers in Materials
The aggregate gradation of asphalt mixture is one of the most important factors affecting the service life of asphalt pavement. In order to study the gradation of asphalt mixture with the best comprehensive performance, this study puts forward a new ...
Fu Zhu, Shengyu Zhang, Wenyi Chen, Hua Rong   +3 more
doaj   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Construction and application of an applicability evaluation system for garlic planters based on fuzzy comprehensive evaluation. [PDF]

PLoS One, 2023
Song H, Dai X.
europepmc   +1 more source