Results 21 to 30 of about 300 (234)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

A note on the fuzzy Xor

Annales Mathematicae Silesianae
In this paper we will try to answer what conditions must be met by the fuzzy Xor to be used for cryptographic purposes. We will also show that defining the fuzzy Xor using other fuzzy connectives is not suitable for this purpose.
Łukasik Radosław
doaj   +1 more source

SPLINE OPTIMIZATION OF SOFT CONNECTIVES IN MACHINE LEARNING MODELS

CLEI Electronic Journal
In this study, the problem of limited accuracy of machine learning models using soft logical connectives is investigated. Such connectives have shown their effectiveness in models with fuzzy initial data. On the one hand, the fundamental disadvantage of
Vyacheslav Kalnitsky, Valery Vilkov
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Linear connections on fuzzy manifolds [PDF]

Classical and Quantum Gravity, 1996
Linear connections are introduced on a series of noncommutative geometries which have commutative limits. Quasicommutative corrections are calculated.
openaire   +3 more sources

Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley   +1 more source

Robustness on Intuitionistic Fuzzy Connectives

TEMA (São Carlos), 2014
<p><!--StartFragment-->The main contribution of this paper is concerned with the robustness of intuitionistic fuzzy connectives in fuzzy reasoning. Starting with an evaluation of the sensitivity in $n$-order functions on the class of intuitionistic fuzzy sets, we apply the results in the intuitionistic $(S,N)$-implication class.
Reiser, R.H.S., Bedregal, B.
openaire   +4 more sources

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Formulation of Fuzzy Implication Modeling Theory

Axioms
This work introduces Fuzzy Implication Modeling Theory, a connective-centered framework that supplies an intermediate structural layer between the class and family levels in the subset of fuzzy implications generated by compositions of the three basic ...
Eleftherios Makariadis, Stefanos Makariadis, Avrilia Konguetsof, Basil K. Papadopoulos   +3 more
doaj   +1 more source