Results 151 to 160 of about 4,537 (304)

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Perbandingan Produksi Kopi Optimum antara Metode Fuzzy-Mamdani dengan Fuzzy-Sugeno (Studi Kasus: PT Sarimakmur Tunggalmandiri)

, 2013
Fuzzy logic is a method for analyzing systems that contain uncertainty. In this study Mamdani method and Sugeno method are in used. Designing the system to obtain the output is done in stage by stage (a) Establishment of a fuzzy set, (b) Application
Samosir, Rianto Pangihutan
core   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Fuzzy adjunctions and fuzzy morphological operations based on fuzzy implications

, 2008
We use conjunctions and fuzzy implications to define fuzzy dilations and fuzzy erosions in fuzzy morphology according to Nachtegael el al. 2003.(1) Further we observe that these fuzzy dilations and fuzzy erosions constitute fuzzy adjunctions that are ...
Kerre, Etienne, Shi, Yun
core  

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

An investigation on Pythagorean fuzzy [Formula: see text] fraction dense space using Pythagorean fuzzy frames. [PDF]

Sci Rep
Gnanachristy NB, Revathi GK.
europepmc   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Searching for Basic Properties Obtaining Robust Implication Operators in Fuzzy Control

, 1998
This paper deals with the problem of searching basic properties for robust implication operators in fuzzy control. We use the word "robust" in the sense of good average behavior in different applications and in combination with different ...
F. Herrera, O. Cordón, A. Peregrín
core  

HADA: A Hybrid Authentication and Dynamic Attribute Access Control Mechanism for the Internet of Things Using Hyperledger Fabric Blockchain. [PDF]

Sensors (Basel)
Alshehri S.
europepmc   +1 more source