Results 191 to 200 of about 75,324 (298)

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Enhancing the LEACH protocol and lightweight chaotic cryptography for secure data transmission in wireless sensor networks. [PDF]

Sci Rep
Zarei M, Fatehi Dindarlou MH, Taghizadeh M, Jamali J.   +3 more
europepmc   +1 more source

Threshold‐Voltage Modulation and N2O Plasma Passivation for Enhanced Retention and Memory Window in Capacitorless 2T0C DRAM Oxide Thin‐Film Transistors

Advanced Science, EarlyView.
Al:ITZO‐based capacitorless 2T0C DRAMs are realized by combining N2O plasma‐induced defect modulation with read‐transistor W/L optimization to suppress leakage and stabilize data storage. This device‐level engineering enables zero‐bias hold operation, retention times exceeding 1000 s, and a 13‐fold expansion of the memory window, demonstrating a ...
Chahwan Yang, Mirinae Lee, Junghoon Han, Sooji Nam   +3 more
wiley   +1 more source

Mitigating Neural Habituation in Insect Bio-Bots: A Dual-Timescale Adaptive Control Approach. [PDF]

Biomimetics (Basel)
Triet LM, Truong Thinh N.
europepmc   +1 more source

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

Advanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su, Qi Qi, Yi Fan, Yubo Wang, Gaoyang Hao, Ka‐Chun Wong, Yunhe Wang, Xiangtao Li   +7 more
wiley   +1 more source

Fuzzy granulation-based wind speed prediction with multi-objective optimization. [PDF]

Sci Rep
Zhang C, Wang J, Li Z.
europepmc   +1 more source

Redox‐Responsive Polymeric Nanocapsules for Enhanced Tumor‐Targeted Delivery of Antimicrobial Peptides

Advanced Science, EarlyView.
This study presents a modular redox‐responsive nanocapsule platform that enables enhanced tumor‐targeted delivery of antimicrobial peptides. Using melittin as an example, the system achieves controlled activation within the tumor microenvironment, improving intratumoral accumulation while minimizing systemic toxicity.
Lin Tang, Yajian Li, Xiaoyin Lv, Jianmei Guo, Yijia Zhang, Yuqi Lin, Kaili Nie, Jian Zeng, Ming Zhang, Qiong Dai   +9 more
wiley   +1 more source

Circular q-rung orthopair fuzzy modeling using Schweizer-Sklar weighted aggregation for water purification strategy selection. [PDF]

Sci Rep
Ali J, N Al-Kenani A, Popa IL.
europepmc   +1 more source

Deep Volumetric Super‐Resolution Imaging in Thick Biological Specimens With Sparse Scanning SIM

Advanced Science, EarlyView.
Sparse scanning structured illumination microscopy (SS‐SIM) extends the axial depth in super‐resolution fluorescence imaging by combining rapid laser scanning, pixel‐addressed intensity modulation, and sCMOS camera detection. SS‐SIM yields 1.6× lateral and 1.7× axial resolution gains over wide‐field microscopy and enables imaging through 300–600 µm ...
Sha An, Xuhong Guo, Zhongxia Cai, Yunze Lei, Kai Wen, Hongfei Suo, Xiaoyu Kong, Gerd Ulrich Nienhaus, Peng Gao   +8 more
wiley   +1 more source

Clustering and Interpretability of Residential Electricity Demand Profiles. [PDF]

Sensors (Basel)
Kallel S, Amayri M, Bouguila N.
europepmc   +1 more source