Results 141 to 150 of about 455,878 (284)

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

open access: yesAdvanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao   +7 more
wiley   +1 more source

Metasurface‐Based Multidimensional Light‐Field Manipulation: From Technologies to Applications

open access: yesAdvanced Science, EarlyView.
Multidimensional metasurfaces enable versatile manipulation of multiple optical degrees of freedom, including phase, amplitude, polarization, wavelength, and orbital angular momentum. This review summarizes their fundamental mechanisms, emerging strategies for multidimensional light‐field control, and key applications in optical computing, imaging ...
Heliang Yin   +6 more
wiley   +1 more source

SpaCut: Transcript‐Aware Morphology Fusion for Robust Cell Segmentation in Subcellular Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Subcellular spatial transcriptomics enables high‐resolution mapping of gene expression within tissues, but accurate cell segmentation is essential for assigning transcripts to individual cells. We present SpaCut, a deep learning framework that integrates transcriptomic features with nucleus‐guided morphological information to precisely delineate cell ...
Yongheng Li, Fangfang Zhu, Wenwen Min
wiley   +1 more source

Fuzzy implications based on quasi-copula and fuzzy negations

open access: yesJournal of Nonlinear Sciences and Applications, 2023
G. Souliotis   +2 more
openaire   +1 more source

The acquisition of negation by L2 German L1 Italian speaker. [PDF]

open access: yes
openThis thesis investigates the acquisition of negation in German by native Italian speaker (L1 Italian) learning German as a second language (L2). The study focuses on high school students in Padua, employing a translation test to collect data on their
FREDDI, MARTA
core  

Highly Linear Perovskite Synapses for Neuromorphic Computing

open access: yesAdvanced Science, EarlyView.
Voltage spikes applied to an Au/ACI‐phase perovskite/ITO memristor emulate the ionic signaling of a biological synapse, generating a tunable postsynaptic current. The vertically aligned perovskite film confines iodide‐vacancy migration, enabling highly linear, and symmetric conductance updates with 100 states and 5.5 aJ per event. Such synapses sustain
Zhongwen Sun   +7 more
wiley   +1 more source

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