Results 141 to 150 of about 160,647 (295)

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Contribution of Fuzzy Minimal Cost Flow Problem by Possibility Programming

Journal of Mathematical Extension, 2010
Using the concept of possibility proposed by zadeh, luhandjula ([4,8]) and buckley ([1]) have proposed the possibility programming. The formulation of buckley results in nonlinear programming problems.
S. Fanati Rashidi, A. A. Noora
doaj  

Ultra‐Wide‐Field Noninvasive Imaging Through Scattering Media Via Physics‐Guided Deep Learning

Advanced Science, EarlyView.
We propose a physics‐guided adaptive dual‐domain learning method for ultra‐wide‐field noninvasive imaging through scattering media, namely UNI‐Net. Our method not only reduces the requirement for real experimental data by an order of magnitude but also enables clear imaging of complex scenes with an ultra‐large field of view, which is 164 times the OME
Lintao Peng, Mingwei He, Jeff Zhu, Sujit K. Sahoo, Liheng Bian, Cuong Dang   +5 more
wiley   +1 more source

Triple‐Mode Ferroelectric Thin‐Film Transistor for Hybrid Electrical–Optical Reservoir Computing

Advanced Science, EarlyView.
A triple‐mode ferroelectric thin‐film transistor is developed by integrating Si3N4/HZO/IGZO layers to realize three independent memory modes: electric long‐term, electric short‐term, and optical short‐term. This single‐device architecture functions as both a reservoir and readout layer, achieving 92.43% MNIST accuracy. It offers a fully hardware‐based,
Hyeonho Lee, Seungjun Lee, Tae‐Hyeon Kim, Yonghee Jeong, Gwangmin An, Minsu Ko, Junsu Yu, Heung Soo Kim, Yang Chai, Sungjun Kim   +9 more
wiley   +1 more source

Developing Micro/Nanostructured Fluidic Mixing Technology for Biomedical Applications

Advanced Science, EarlyView.
This review critically evaluates how micro/nanostructured mixing technologies are redefining biomedical research. By synergizing fundamental analysis, numerical modeling, structural design, and external field manipulation, these systems attain unprecedented control over mass transport.
Junkai Wang, Hanxu Chen, Yile Fang, Yuanjin Zhao   +3 more
wiley   +1 more source

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

Advanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen, Jiahui Xie, Yi Liao, Junyu Li, Longqi Liu, Xin Gao, Hongmin Cai   +6 more
wiley   +1 more source

Research on a fuzzy programming model and algorithm for berth allocation considering time-varying water depth. [PDF]

Sci Rep
Liu D, Li B, Li M, Lei Y, Yu P, Tan C.
europepmc   +1 more source

Tunable Dynamics via Dual‐Ion Modulation for Event‐based Data Processing Using a Highly Uniform and Self‐Rectifying Memristor Array

Advanced Science, EarlyView.
Tunable dynamics of an interface‐type memristor array enabled by dual‐ion modulation through Ag nanoclusters are demonstrated. A 32 × 32 one‐resistor (1R) array exhibits 100% yield with high temporal/spatial uniformity (<3%) and a rectification ratio of 105.
Yoonho Cho, Dawon Kim, Jeonghong Lee, Dae‐won Kim, See‐On Park, Jongmin Bae, Taehwan Jang, Shinhyun Choi   +7 more
wiley   +1 more source

A bi-objective robust fuzzy programming model to configure a microgrid-based cement supply chain. [PDF]

Sci Rep
Tirkolaee EB, Golpîra H, Bahramara S, Javanmardan A.   +3 more
europepmc   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source