ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen +22 more
wiley +1 more source
Federated Learning Based on Fuzzy Fusion Rules for Chemical Production Process Fault Diagnosis. [PDF]
Xu Y, Yang W, Du S, Zhang M.
europepmc +1 more source
Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond
Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu +5 more
wiley +1 more source
Optimizing Budget Allocation for Digital Health Investments Using Metaheuristic Algorithms: A Cost-Impact Analysis for Public Health Systems. [PDF]
Dayi F +4 more
europepmc +1 more source
Task‐adaptive programmable optics enables label‐free virtual staining through optical‐attention‐guided acquisition and reconstruction. By optimizing wavelength, illumination angle, exposure time, and imaging depth, the framework learns task‐relevant optical measurements, generating clinically interpretable virtual stains with improved fidelity, non ...
Tianyue He +13 more
wiley +1 more source
Precision improvement for indoor positioning based on fuzzy inference system with ultra-wideband wireless communications. [PDF]
Lee SH, Chang SW, Huang YF, Sheu YH.
europepmc +1 more source
Matrix Stiffness Induces Endothelial Network Senescence
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song +6 more
wiley +1 more source
Uncertainty-resilient control of large-scale industrial IoT networks via learning-guided fuzzy intelligence. [PDF]
Duan C, Wang Y, Zhang P, Li S, Luo S.
europepmc +1 more source
Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG
Simultaneous MEG and stereotactic EEG (SEEG) recordings provide a direct validation framework for MEG source imaging in focal epilepsy. Virtual SEEG signals derived from MEG reconstructions reveal significant agreement with intracranial measures of spike localization, resting‐state oscillations, and functional connectivity, while also identifying ...
Jawata Afnan +10 more
wiley +1 more source
Fuzzy control and its application to a pH process [PDF]
In the chemical industry, the control of pH is a well-known problem that presents difficulties due to the large variations in its process dynamics and the static nonlinearity between pH and concentration. pH control requires the application of advanced
Huang, Kuo-En
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