Results 211 to 220 of about 96,386 (319)

MOEA/D‐based multi‐row facility layout optimisation method with discontinuity perceiving of the Pareto front

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
Abstract In a multi‐row facility layout problem (MRFLP), facilities are arranged in more than one row under the limited layout area. Considering different layout factors, various extensions of MRFLP have been modelled. However, the orientation of input/output (I/O) point in a facility, as a key factor that plays a direct impact on flow cost, is seldom ...
Yinan Guo   +5 more
wiley   +1 more source

From Ambiguous Queries to Verifiable Insights: A Task‐Driven Framework for LLM‐Powered SOC Analysis⋆

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Security operations centre (SOC) analysts must investigate alerts, correlate threat intelligence and interpret heterogeneous telemetry under tight timing constraints. Although large language models (LLMs) offer strong understanding capabilities, directly applying them to SOC environments remains challenging due to semantic ambiguity in analyst
Huan Zhang   +5 more
wiley   +1 more source

Cryo‐EM structure of ALC1 in an open conformation bound to a PARylated nucleosome

open access: yesActa Crystallographica Section D, EarlyView.
Reanalysis of a publicly available cryo‐EM dataset identifies a new conformation of the oncogenic chromatin remodeler ALC1/CHD1L bound to a PARylated nucleosome. This new structure reveals the position of the macro domain in the complex, and may help to understand the large conformational change leading to the activation of ALC1.Nucleosomes are the ...
Hannah R. Bridges   +3 more
wiley   +1 more source

Resonance and Psychic Affirmation: A Comparison of Hartmut Rosa's and Daniel Haybron's Conceptions of Human Happiness

open access: yesConstellations, EarlyView.
ABSTRACT The paper compares Hartmut Rosa's resonance theory of “the good life” and Daniel Haybron's psychic affirmation theory of “happiness,” which he differentiates, as a descriptive notion, from “well‐being” as an evaluative notion. Haybron suggests that a central determinant of happiness has to be the somewhat reliable occurrence of positive ...
Ole Höffken
wiley   +1 more source

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