Results 31 to 40 of about 18,237 (266)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

Reliability-Based Robust Online Constructive Fuzzy Positioning Control of a Turret-Moored Floating Production Storage and Offloading Vessel

open access: yesIEEE Access, 2018
In this paper, a mathematical model for a floating production storage and offloading (FPSO) vessel is introduced at first. Considering the unknown system parameters and environmental disturbances, we proposed a reliability-based robust online ...
Yulong Tuo, Yuanhui Wang, Shasha Wang
doaj   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Optimal Genetic Design of Type-1 and Interval Type-2 Fuzzy Systems for Blood Pressure Level Classification

open access: yesAxioms, 2019
The use of artificial intelligence techniques such as fuzzy logic, neural networks and evolutionary computation is currently very important in medicine to be able to provide an effective and timely diagnosis. The use of fuzzy logic allows to design fuzzy
Juan Carlos Guzmán   +3 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

A New Opinion Mining Method based on Fuzzy Classifier and Particle Swarm Optimization (PSO) Algorithm

open access: yesCybernetics and Information Technologies, 2018
Opinion Mining or Sentiment Analysis is the task of extracting people final opinion about something through their unstructured sentiments. The Opinion Mining process is as follows: first, product features which are most important to a user are extracted ...
Bordbar Samira, Shamsinejad Pirooz
doaj   +1 more source

Selection of Satisfied Association Rules via Aggregation of Linguistic Satisfied Degrees

open access: yesIEEE Access, 2019
Many association rule mining algorithms have been well-established, such as Apriori, Eclat, FP-Growth, or LCM algorithms. However, the challenge is that the huge size of association rules is extracted by using these algorithms, and it is difficult for ...
Fangling Ren, Zheng Pei, Kehong Wu
doaj   +1 more source

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