Results 271 to 280 of about 500,880 (319)

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

open access: yesAggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky   +3 more
wiley   +1 more source

Boosting the Antimicrobial Activity of Quaternary Ammonium Photosensitizers by Janus‐Type AIE Luminogens

open access: yesAggregate, EarlyView.
Novel quaternary ammonium AIE luminogens (AIEgens) with symmetric and Janus structures are rationally designed and prepared for bacteria killings. The integration of experimental and theoretical studies discloses that the Janus‐type AIEgen interacts better with bacterial membranes and shows stronger membrane perturbation, demonstrating superior ...
Dongyang Fan   +7 more
wiley   +1 more source

A Universal Doping Strategy for Boosting Luminescence Efficiency of Blue‐Emitting Hybrid Zn Halides as Ultrastable and Underwater Scintillators

open access: yesAggregate, EarlyView.
A Pb2+‐doping method is demonstrated to be a universal strategy to realize near‐unity photoluminescence quantum yield and high water‐resistance stability for a family of blue‐emitting zero‐dimensional Zn2+‐based halides through increasing the exciton binding energy and carrier density.
Zhi‐Wei Chen   +8 more
wiley   +1 more source

Domain‐Aware Implicit Network for Arbitrary‐Scale Remote Sensing Image Super‐Resolution

open access: yesAdvanced Intelligent Discovery, EarlyView.
Although existing arbitrary‐scale image super‐resolution methods are flexible to reconstruct images with arbitrary scales, the characteristic of training distribution is neglected that there exists domain shift between samples of various scales. In this work, a Domain‐Aware Implicit Network (DAIN) is proposed to handle it from the perspective of domain
Xiaoxuan Ren   +6 more
wiley   +1 more source

Machine‐Learning‐Based, Feature‐Rich Prediction of Alumina Microstructure from Hardness

open access: yesAdvanced Intelligent Discovery, EarlyView.
Herein, high‐performance generative adversarial network (GAN), named ‘Microstructure‐GAN’, is demonstrated. After training, the high‐fidelity, feature‐rich micrographs can be predicted for an arbitrary target hardness. Microstructure details such as small pores and grain boundaries can be observed at the nanometer scale in the predicted 1000 ...
Xiao Geng   +10 more
wiley   +1 more source

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