Results 221 to 230 of about 40,710 (290)

Emodin and physcion alleviate cholestatic liver injury by targeting FXR: hepatoprotective components identified in processed <i>Polygonum multiflorum</i> Thunb. using a comprehensive two-dimensional biochromatography system. [PDF]

Front Pharmacol
Li Z, Gu Y, Yang J, Wang S, Li S, Chen P, Yao R, Liu F, Wang Y, Wang R, Yuan Y.   +10 more
europepmc   +1 more source

Role and progression of bile acid metabolism in mediating Th17/Treg homeostasis in inflammatory bowel disease. [PDF]

iScience
Yue S, Tan Y, Gong L, Liao F.
europepmc   +1 more source

Pleiotropic immunoregulation by bile acids in pathophysiology. [PDF]

Front Immunol
Lin BS, Yin MY, Xie SA, Li P, Li X.
europepmc   +1 more source

7-Ketolithocholic Acid Exerts Anti-Renal Fibrotic Effects Through FXR-Mediated Inhibition of TGF-β/Smad and Wnt/β-Catenin Pathways. [PDF]

Pharmaceuticals (Basel)
Guo Q, Peng L, Zhang J, Hu J, Wang Y, Wei J, Zhang Z.   +6 more
europepmc   +1 more source

Disruption of bile acid homeostasis potentiates Paneth cell ablation by activating the intestinal Farnesoid X receptor in necrotizing enterocolitis. [PDF]

NPJ Biofilms Microbiomes
Xiong J, Guo T, Gao T, Aierken Y, Chong Q, Lv Z, Lu L.   +6 more
europepmc   +1 more source

Bile acid signaling mediates gut microbiota regulation of host lipid metabolism. [PDF]

Front Microbiol
Liu M, He C, Lv X, Zheng W, Yin J, Li Y, Ma J.   +6 more
europepmc   +1 more source

<i>Akkermansia muciniphila</i> alleviates experimental colitis through FXR-mediated repression of unspliced XBP1. [PDF]

mSystems
Bu F, Zhang K, Song B, He L, Lu Z, Yuan X, Chen C, Jiang F, Tao Y, Zhang W, Zhang D, Chen Y, Wang Q.   +12 more
europepmc   +1 more source

Structure-Based Discovery of Obeticholic Acid Derivatives as Novel Farnesoid X Receptor Partial Agonists with Improved Selectivity and Reduced Off-Target Effects. [PDF]

ChemMedChem
Passeri D, Cerra B, Carotti A, Greco F, Piermarini S, Colliva C, Liscio P, De Franco F, Adorini L, Erickson MR, Pellicciari R, Gioiello A.   +11 more
europepmc   +1 more source

Matrine improves bile acid metabolism and reduces inflammatory and oxidative stress in colitis via the JAK2 pathway. [PDF]

Chin Med
Jiang ZX, Chen XL, Sun Q, Yang LC, Zhang YW, Wu Q, Yao HC, Zhang D, Yuan LW.   +8 more
europepmc   +1 more source

Prevention of Cholestatic Liver Disease Through BCL6-FXR Enterohepatic Crosstalk. [PDF]

Cell Mol Gastroenterol Hepatol
Fruzyna E, Sommars MA, Omura Y, Yarnoff KM, Wang JC, Futtner CR, Green RM, Barish GD.   +7 more
europepmc   +1 more source