Results 171 to 180 of about 2,807 (196)

Neuroimaging Findings in FXTAS

2016
In this chapter, we review the neuroimaging findings associated with fragile X-associated tremor/ataxia syndrome (FXTAS). We review what is currently known about radiological signs of the disorder including both white matter lesions and mild to severe cortical loss.
Emily S. Halket, Jun Yi Wang, David Hessl, Susan M. Rivera   +3 more
openaire   +1 more source

Treatment and Management of FXTAS

2010
Fragile X-associated tremor/ataxia syndrome (FXTAS) affects older adult carriers of the FMR1 premutation and can be associated with a broad array of clinical symptoms and presentations including tremor, ataxia, parkinsonism, executive function disturbance and dementia, psychiatric symptoms of anxiety, depression and disinhibition, peripheral neuropathy,
Elizabeth Berry-Kravis, Deborah A. Hall, Maureen A. Leehey, Randi J. Hagerman   +3 more
openaire   +1 more source

Clinical Neurological Phenotype of FXTAS

2010
The classic presentation of fragile X-associated tremor/ataxia syndrome (FXTAS) is an aging man with progressive cerebellar gait ataxia, kinetic tremor, mild parkinsonism, cognitive decline, especially executive dysfunction and short-term memory deficiency, and peripheral neuropathy. Autonomic dysfunction and mood/anxiety disorders may be present.
Maureen A. Leehey, Elizabeth Berry-Kravis, Christopher G. Goetz, Randi J. Hagerman   +3 more
openaire   +1 more source

Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS)

Mental Retardation and Developmental Disabilities Research Reviews, 2004
AbstractCarriers of fragile X mental retardation 1 (FMR1) premutation alleles (55 to 200 CGG repeats) are generally spared the more serious neurodevelopmental problems associated with the full‐mutation carriers (>200 repeats) of fragile X syndrome.
Paul J, Hagerman, Randi J, Hagerman
openaire   +2 more sources

Genotype/Phenotype Relationships in FXTAS

2010
In this chapter we explore the effects of molecular measures of the FMR1 gene on clinical, cognitive, radiological, and pathological phenotypes associated with fragile X-associated tremor/ataxia syndrome (FXTAS). In addition to reviewing the FXTAS phenotype, we will also present methods that have been developed for quantifying severity of FXTAS ...
Emily G. Allen, Maureen A. Leehey, Flora Tassone, Stephanie Sherman   +3 more
openaire   +1 more source

FXTAS: Neuropsychological/Neuropsychiatric Phenotypes

2010
This chapter reviews research on the neuropsychological and psychiatric signs and symptoms of the fragile X-associated tremor/ataxia syndrome (FXTAS). We summarize what is known about cognition and psychological/psychiatric functioning in affected individuals, as well as asymptomatic carriers of the FMR1 premutation.
Jim Grigsby, Angela G. Brega, Andreea L. Seritan, James A. Bourgeois   +3 more
openaire   +1 more source

Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)

2019
Individuals carrying an FMR1 expansion between 55 and 200 CGG repeats, are at risk of developing the Fragile X-associated tremor/ataxia syndrome (FXTAS), a late onset neurodegenerative disorder characterized by cerebellar gait ataxia, intentional tremor, neuropathy, parkinsonism, cognitive decline, and psychological disorders, such as anxiety and ...
Marwa, Zafarullah, Flora, Tassone
openaire   +2 more sources

FXTAS syndrome: Neuropsychiatric features

Journal of the Neurological Sciences, 2021
Charfi Rihab, Khadija Sonda Moalla, Nouha Farhat, Olfa Hdiji, Salma Sakka, Sawsan Daoud, Hanene Hajkacem, Mariem Damak, Chokri Mhiri   +8 more
openaire   +1 more source

FXTAS

Neurology Today, 2005
openaire   +1 more source

The Pathology of FXTAS

2010
Claudia M. Greco, Michael R. Hunsaker, Robert F. Berman   +2 more
openaire   +1 more source