Results 131 to 140 of about 188,088 (221)

Loss of PTEN as an Independent Poor Prognosis Indicator in Lung Adenocarcinoma, but Not in Squamous Cell Carcinoma, Is Associated with an Immunosuppressive Tumor Microenvironment and Distinct Co-Mutational Profiles. [PDF]

Med Sci (Basel)
Houry M, Silva SJ, Artola M, Behrens C, Politi K, Wistuba I, Montuenga L, Exposito F, Calvo A.   +8 more
europepmc   +1 more source

Implementation of Machine Learning Models to Predict Functionality of Pea Flour From Its Composition

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives The goal of this research was to examine the relationship between the composition and functionality of pea flour using the following machine learning algorithms: linear regression, partial least squares regression (PLSR), Gaussian process regression (GPR), support vector regression, gradient‐boosted decision trees ...
Colten N. Nickerson, Sarah Hogarth, Andrea K. Stone, Gene C. Arganosa, Pankaj Bhowmik, Tom D. Warkentin, Jordan Ubbens, Michael T. Nickerson   +7 more
wiley   +1 more source

Inactivation of <i>BAP1</i> and the Hippo Pathway Characterizes the Genomic Alterations of Peritoneal Mesothelioma. [PDF]

Life (Basel)
Samuels M, Williams M, Hasan A, Rafie S, Saglimbeni GS, Hsia B, Nair S, Aeilias S, Tauseef A.   +8 more
europepmc   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Loop-mediated isothermal amplification (LAMP) assay for identification of Australian Plague Locust (APL), Chortoicetes terminifera (Walker, 1870). [PDF]

Sci Rep
Rako L, Martoni F, Selleck C, Kearney MR, Rodoni BC, Blacket MJ.   +5 more
europepmc   +1 more source

Polarity on Demand: Nucleophilic, Electrophilic, and Ambiphilic Reactivity at a 9,10‐Dihydro‐9,10‐Disilaanthracene Platform

Chemistry – A European Journal, EarlyView.
A 9,10‐dihydro‐9,10‐disilaanthracene platform was efficiently synthesized and features intrinsically electrophilic Si sites. Upon stepwise reductive Si─H bond cleavage, these Si sites are converted into nucleophilic centers. This controlled polarity switching also enables ambiphilic reactivity within a homo‐heteroelement framework.
Moritz Schmidt, Alexander Virovets, Eugenia Peresypkina, Hans‐Wolfram Lerner, Matthias Wagner   +4 more
wiley   +1 more source

Mutational Spectrum of T-Cell Large Granular Lymphocytic Leukemia: Insights From the AACR Project GENIE Consortium. [PDF]

Cancer Genomics Proteomics
Upadhyayula BS, Saglimbeni GS, Gobel E, Gobel A, Morris TJ, Surendra A, Hsia B, Sood A, Tauseef A.   +8 more
europepmc   +1 more source

Synthesis of Oligonucleotide Conjugates Employing a Diselenide Linker

Chemistry – A European Journal, EarlyView.
ABSTRACT In this study, we report the synthesis of an alkylene linker containing a terminal 2‐cyanoethyl protected selenium functionality for coupling at the 5'‐end of an oligonucleotide by solid phase synthesis for the preparation of oligonucleotide conjugates.
Shivam Tikoo, Anne M. Noronha, Christopher J. Wilds   +2 more
wiley   +1 more source

Genomic Landscape of Thymic Carcinoma: A Large-Scale Analysis of Somatic Mutations, Demographic Disparities, and Metastatic Drivers from the AACR Project GENIE^® Cohort. [PDF]

Curr Issues Mol Biol
Chudziak AV, Morris TJ, Maliy D, Saglimbeni GS, Surendra A, Hsia B, Li H, Tauseef A.   +7 more
europepmc   +1 more source

Synthesis and characterization of amphiphilic nitroxide 1,1,3,3–tetraethylisoindoline–2–oxyl–5–sodium sulfonate (TEIOSNa)

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract The synthesis and characterization of an amphiphilic nitroxide to be used as a controlling agent in a nitroxide‐mediated living radical polymerization in aqueous dispersion media is presented. In the first stage of nitroxide synthesis (phthalimide protection), two reaction methods were employed: traditional and microwave.
Enrique García‐Leal, Martha Eugenia Albores Velasco, René O. Vargas, Rubén Mil‐Martínez   +3 more
wiley   +1 more source