Results 181 to 190 of about 300,059 (216)

MurNAc‐Based Electrophilic Inhibitors of O‐Acetylpeptidoglycan Esterase (Ape): Design, Synthesis, and Kinetic Evaluation

open access: yesChemistry – A European Journal, EarlyView.
A series of N‐acetylmuramic acid (MurNAc)‐based electrophilic inhibitors targeting Ape esterase was synthesized. Their inhibitory potency ranged from micromolar to submillimolar. The study probed binding contributions of stem peptide extension, replacing the anomeric methyl group with a benzyl, and α‐fluorination of the carbonyl to enhance ...
Dmytro Voskoboinyk, Martin E. Tanner
wiley   +1 more source

Diffusion-Based Protein Structure Design: Geometric Modelling, Validation Strategies, and Thermodynamic Challenges. [PDF]

open access: yesInt J Mol Sci
Li W   +10 more
europepmc   +1 more source

Synthesis and characterization of amphiphilic nitroxide 1,1,3,3–tetraethylisoindoline–2–oxyl–5–sodium sulfonate (TEIOSNa)

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract The synthesis and characterization of an amphiphilic nitroxide to be used as a controlling agent in a nitroxide‐mediated living radical polymerization in aqueous dispersion media is presented. In the first stage of nitroxide synthesis (phthalimide protection), two reaction methods were employed: traditional and microwave.
Enrique García‐Leal   +3 more
wiley   +1 more source

Bridging the Gap: Medical Schools' Transition to Residency Courses and their Graduates' Readiness for Residency. [PDF]

open access: yesMed Sci Educ
Heidemann LA   +7 more
europepmc   +1 more source

Gibbs energy minimization thermodynamics for CO2 capture by aqueous amines: Conservation laws, concentration variables, and parameter consistency

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
We clarify how Gibbs‐energy‐minimization models for aqueous‐amine CO2 capture fail when conservation constraints and concentration conventions are inconsistent. Exact standard‐state conversions and Reaktoro case studies show that P(CO2)‐loading fits can mask non‐unique parameters and wrong speciation, motivating complete water‐inclusive formulations ...
William R. Smith   +2 more
wiley   +1 more source

Extended batch adsorber analogue model (e‐BAAM) for rapid evaluation of CO2 capture pressure swing adsorption cycles

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract This work presents a simplified extended‐batch adsorber analogue model (e‐BAAM) to quantify key performance metrics such as purity, recovery, and energy trends for various pressure swing adsorption (PSA) process cycles for CO2$$ {\mathrm{CO}}_2 $$ capture.
Gwyneth Liske, Arvind Rajendran
wiley   +1 more source

Waste activated sludge high‐rate treatment of septage: Stabilization phase trials and comparison with winery wastewater treatment

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Performance evaluation of the waste activated sludge high‐rate (WASHR) process for septic wastewater treatment. Abstract The waste‐activated sludge high‐rate (WASHR) process is evaluated as a batch‐mode pre‐treatment for actual septage using a high‐rate contact stabilization (HRCS) approach.
Arman Shirali   +2 more
wiley   +1 more source

STK11 Mutations and Deletions Define an Aggressive Molecular Subgroup of Cervical Adenocarcinoma. [PDF]

open access: yesCancer Med
Robinson EW   +22 more
europepmc   +1 more source

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