Results 61 to 70 of about 276,085 (274)

A New Family of Gauges in Linearized General Relativity [PDF]

, 1998
For vacuum Maxwell theory in four dimensions, a supplementary condition exists (due to Eastwood and Singer) which is invariant under conformal rescalings of the metric, in agreement with the conformal symmetry of the Maxwell equations.
Aronszajn N, Birrell N D, Cosimo Stornaiolo, Duff M J, Esposito G, Esposito G, Fulling S A, Giampiero Esposito, Gilkey P B, Hawking S W, Jackson J D, Paneitz S, Penrose R, Penrose R, Penrose R, Ward R S   +15 more
core   +4 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Fundamental stellar parameters and metallicities from Bayesian spectroscopy. Application to low- and high-resolution spectra

, 2014
We present a unified framework to derive fundamental stellar parameters by combining all available observational and theoretical information for a star.
Bergemann, Maria, Schönrich, Ralph
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Seasonal variations of triterpene acid contents in Viscum album L. on typical host trees of Hyrcanian forests

Scientific Reports, 2023
Viscum album L. (mistletoe) is a semiparasitic plant of the Santalaceae family. A valuable group of bioactive compounds in mistletoe are triterpene acids (TTAs), which possess anti-inflammatory and anticancer properties.
Arina Soursouri, Seyed Mohsen Hosseini, Farnoosh Fattahi   +2 more
doaj   +1 more source

Statistical mechanics of budget-constrained auctions

, 2009
Finding the optimal assignment in budget-constrained auctions is a combinatorial optimization problem with many important applications, a notable example being the sale of advertisement space by search engines (in this context the problem is often ...
A Braunstein, Andelman N Mansour Y, Azar Y, Bayati M, F Altarelli, Garg R, J Realpe-Gomez, Kirkpatrick S Gelatt C D Vecchi M P, Marinari E, Matoušek J, Montanari A, R Zecchina   +11 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Barium in coal and coal combustion products: Distribution, enrichment and migration

Energy Exploration & Exploitation, 2022
Coal triggering pollution caused by the emission of harmful substances in the process of coal combustion has been paid more and more attention. Barium is a ubiquitous heavy metal element in coal.
Huidi Hao, Minmin Zhang, Jinxi Wang, Zhiheng Fu, Panchal Balaji, Shuting Jiang   +5 more
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

„Eine Allianz der evidenzbasiert Entscheidenden gegen Populismus“

Monitor Versorgungsforschung
Im Doppel-Titelinterview zum Jahresstart 2024 mit „Monitor Versorgungsforschung“ diskutieren Prof. Josef Hecken, der unparteiische Vorsitzende des Gemeinsamen Bundesausschusses (G-BA), und Univ.-Prof. Dr. med.
Prof. Josef Hecken, Univ.-Prof. Dr. med. Wolfgang Hoffmann, Peter Stegmaier   +2 more
doaj   +1 more source