Results 51 to 60 of about 830,970 (279)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Environment InternationalDipentyl phthalate (DPeP) is a potent male reproductive toxicant that reduces fetal testicular testosterone production and induces abnormal fetal testis morphology, including multinucleated germ cells (MNGs).
Maansi V. Gupta +6 more
doaj +1 more source
Development of an Automatic Robotic Procedure for Machining of Skull Prosthesis
Robotics, 2020 The project presented in this paper develops within the field of automation in the medical-surgical sector. It aims at automating the process for the realization of prosthetic devices for the skull in cranioplasty, following a craniotomy intervention for
Kevin Castelli +2 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Orbital: The Electronic Journal of ChemistryIn this study two novel benzazocine derivatives containing potentially anticancer properties, (a) NAOP-12 (C24H16N4) & (b) NEMKH-12 (C25H18N4), were investigated utilizing quantum computational technique. The equilibrium geometries of the compounds have
Tanveer Hasan +4 more
doaj +1 more source
PD-sets for codes related to flag-transitive symmetric designs [PDF]
Transactions on Combinatorics, 2018 For any prime $p$ let $C_p(G)$ be the $p$-ary code spanned by the rows of the incidence matrix $G$ of a graph $Gamma$. Let $Gamma$ be the incidence graph of a flag-transitive symmetric design $D$.
Dean Crnkovic, Nina Mostarac
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
3D hybrid wound devices for spatiotemporally controlled release kinetics [PDF]
, 2012 This paper presents localized and temporal control of releasekinetics over 3-dimensional (3D) hybridwounddevices to improve wound-healing process. Imaging study is performed to extract wound bed geometry in 3D.
Koc, Bahattin +3 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Machine Vision Implementation in Rapid PCB Prototyping [PDF]
, 2011 Image processing, the heart of machine vision, has proven itself to be an essential part of the industries today. Its application has opened new doorways, making more concepts in manufacturing processes viable.
Murijanto, Y. S. (Yosafat) +2 more
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