Results 51 to 60 of about 852,371 (247)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Environment InternationalDipentyl phthalate (DPeP) is a potent male reproductive toxicant that reduces fetal testicular testosterone production and induces abnormal fetal testis morphology, including multinucleated germ cells (MNGs).
Maansi V. Gupta +6 more
doaj +1 more source
Development of an Automatic Robotic Procedure for Machining of Skull Prosthesis
Robotics, 2020 The project presented in this paper develops within the field of automation in the medical-surgical sector. It aims at automating the process for the realization of prosthetic devices for the skull in cranioplasty, following a craniotomy intervention for
Kevin Castelli +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Orbital: The Electronic Journal of ChemistryIn this study two novel benzazocine derivatives containing potentially anticancer properties, (a) NAOP-12 (C24H16N4) & (b) NEMKH-12 (C25H18N4), were investigated utilizing quantum computational technique. The equilibrium geometries of the compounds have
Tanveer Hasan +4 more
doaj +1 more source
PD-sets for codes related to flag-transitive symmetric designs [PDF]
Transactions on Combinatorics, 2018 For any prime $p$ let $C_p(G)$ be the $p$-ary code spanned by the rows of the incidence matrix $G$ of a graph $Gamma$. Let $Gamma$ be the incidence graph of a flag-transitive symmetric design $D$.
Dean Crnkovic, Nina Mostarac
doaj +1 more source
Designing a dexterous reconfigurable packaging system for flexible automation [PDF]
, 2003 This paper presents a design for a reconfigurable packaging system that can handle cartons of different shape and sizes and is amenable to ever changing demands of packaging industries for perfumery and cosmetic products.
Crowder, Richard M., Dubey, Venketesh N.
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Machine Vision Implementation in Rapid PCB Prototyping [PDF]
, 2011 Image processing, the heart of machine vision, has proven itself to be an essential part of the industries today. Its application has opened new doorways, making more concepts in manufacturing processes viable.
Murijanto, Y. S. (Yosafat) +2 more
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source