Results 51 to 60 of about 12,884,416 (263)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Nature CommunicationsConversion electrodes offer higher reversible capacity and lower cost than conventional intercalation chemistry electrodes, but suffer from kinetic limitation and large volume expansion.
Shengfeng Zhang +13 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Entropy production in an energy balance Daisyworld model
, 2008 Daisyworld is a simple mathematical model of a planetary system that exhibits self-regulation due to the nature of feedback between life and its environment.
Dyke, J. G.
core +1 more source
On foundation of generative statistics with G-entropy: a gradient-based approach
This paper explores the interplay between statistics and generative artificial intelligence. Generative statistics, an integral part of the latter, aims to construct models that can generate efficiently and meaningfully new data across the whole of the (usually high dimensional) sample space, e.g. a new photo.
Cheng, Bing, Tong, Howell
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Journal of High Energy PhysicsAccording to the GEVAG (Generalized Entropy Varying-G) framework, any modification to the Bekenstein-Hawking area law would also lead to a varying-G gravity theory in which the effective gravitational constant G eff becomes area-dependent. Among a myriad
Chen-Hao Wu, Yen Chin Ong
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Entropy Analysis of Short-Term Heartbeat Interval Time Series during Regular Walking
Entropy, 2017 Entropy measures have been extensively used to assess heart rate variability (HRV), a noninvasive marker of cardiovascular autonomic regulation. It is yet to be elucidated whether those entropy measures can sensitively respond to changes of autonomic ...
Bo Shi +4 more
doaj +1 more source
Double brane holographic model dual to 2d ICFTs
Journal of High Energy Physics, 2022 A minimal single brane holographic model can be used as a dual to 2d conformal interfaces (ICFTs) to calculate the transmission coefficient T $$ \mathcal{T} $$ of energy transported across the defect as well as boundary entropy log g, the additional ...
Saba Asif Baig, Andreas Karch
doaj +1 more source