Results 81 to 90 of about 12,884,416 (263)

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Acknowledgement to Reviewers of Entropy in 2016

open access: yes, 2017
The editors of Entropy would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2016.[...
Entropy Editorial Office
core   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

GWAS-Significant Loci and Uterine Fibroids Risk: Analysis of Associations, Gene-Gene and Gene-Environmental Interactions

open access: yesFrontiers in Bioscience-Scholar
Background: Uterine fibroids (UF) is the most common benign tumour of the female reproductive system. We investigated the joint contribution of genome-wide association studies (GWAS)-significant loci and environment-associated risk ...
Liubov Ponomareva   +2 more
doaj   +1 more source

On Properties of Distance-Based Entropies on Fullerene Graphs

open access: yesEntropy, 2019
In this paper, we study several distance-based entropy measures on fullerene graphs. These include the topological information content of a graph I a ( G ) , a degree-based entropy measure, the eccentric-entropy I f σ ( G ...
Modjtaba Ghorbani   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The minimum local cross-entropy criterion for inferring risk-neutral price distributions from traded options prices [PDF]

open access: yes, 2004
A quantity known as the Local Cross-Entropy (LCE) for a density is proposed, defined to be the local derivative of the Cross-Entropy between a density and a ’kernel-smoothed’ version of itself, with respect to bandwidth of the smoothing.
Edelman, David
core   +1 more source

Phase prediction, microstructure and high hardness of novel light-weight high entropy alloys

open access: yesJournal of Materials Research and Technology, 2019
Guided by CALPHAD modeling, low-density and multiphase three novel High Entropy Alloys (HEAs), Al40Cu15Cr15Fe15Si15, Al65Cu5Cr5Si15Mn5Ti5 and Al60Cu10Fe10Cr5Mn5Ni5Mg5 were produced by large scale vacuum die casting. A mixture of simple and complex phases
Jon Mikel Sanchez   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

FIRE-G: Entropy-Driven Field-Induced Radiant Gravity

open access: yes
This work presents FIRE-G: Field-Induced Radiant Gravity, a novel theoretical framework explaining galactic rotation, gravitational lensing, and cosmic expansion without dark matter or dark energy. Supporting plots, figures, and simulations are included.
openaire   +2 more sources

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