Results 51 to 60 of about 282,423 (243)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Lipschitz Analysis of g-Phase Retrievable Frames [PDF]

Sahand Communications in Mathematical Analysis
A g-phase retrievable frame is a $\lambda$-phase retrievable frame in finite dimensional Hilbert space $\mathcal{H}_n$, where $\lambda$ is an special function, which is called phase coefficient function.
Mohammad Ali Hasankhani Fard
doaj   +1 more source

Some Generalizations of Relay Fusion Frames and F,G-Relay Fusion Frames in Hilbert C∗-Modules

Journal of Mathematics, 2023
The relay fusion frame proposed by Hong and Li is an extension of a fusion frame that has many applications in science. In this study, we introduce relay fusion frames in Hilbert C∗-modules very naturally and shift some common attributes of fusion frames
Xiujiao Chi, Guoqing Hong, Pengtong Li
doaj   +1 more source

Weaving g-Frames for Operators

Kragujevac Journal of Mathematics
Bemrose et al. introduced weaving frames and later, Deepshikha et al. generalized them to weaving K-frames. In this note, as a generalization of these notions, we introduce approximate K-duals and investigate the properties of K-g-frames and weaving K-g-frames. We show that woven K-g-frames and weakly woven K-g-frames coincide.
Khosravi, A., Banyarani, J. S.
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

K-bi-g-frames in Hilbert spaces [PDF]

Journal of Algebraic Systems
The notion of K-frames generalizes ordinary frames in that the lower frame bound applies only to elements within the range of K. This paper will introduce the new concept of K-bi-g-frames for Hilbert spaces.
Mohamed Rossafi, Abdelilah Karara
doaj   +1 more source

Coherent Frames [PDF]

Sahand Communications in Mathematical Analysis, 2018
Frames which can be generated by the action of some operators (e.g. translation, dilation, modulation, ...) on a single element $f$ in a Hilbert space, called coherent frames.
Ataollah Askari Hemmat, Ahmad Safapour, Zohreh Yazdani Fard   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

$E$-$g$-frames

In the present paper, we introduce the notion of $E$-$g$-frames for a separable Hilbert spaces $\mathcal H$, where $E$ is an invertible infinite matrix mapping on the Hilbert space $\mathop\oplus\limits_{n=1}^{\infty}\mathcal H_n$. We study some prperties of $E$-$g$-frames.
Lal Shateri, Tayebe, Hedayatirad, Hassan
openaire   +2 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source