Results 101 to 110 of about 1,153,523 (263)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Specific Separation of Chromium(III) from Mixture with numerous Metal Ions by Tic on Silica Gei-G Layers in HCI and DMSO- HCI systems.

, 1986
Department of Chemistry, Hindu College Monadabad-244 001 Manuscript received 16 April 1985, revised 12 August 1986, accepted 5 September 1986 Specific Separation of Chromium(III) from Mixture with numerous Metal Ions by Tic on Silica Gei-G Layers in HCI and DMSO- HCI systems.
S. D. SHARMA, B. M. SETHI
openaire   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Maturation stress generation starts before the formation of the G-layer in poplar tension wood

, 2009
Tension wood is widespread in organs of woody plants. During its formation, it generates large tensile mechanical stress, called maturation stress [1]. This stress performs essential biomechanical functions such as optimizing the stem mechanical resistance, performing adaptive movements and ensuring long-term stability of growing plants.
Clair, Bruno, Alméras, Tancrède, Pilate, Gilles, Jullien, Delphine, Sugiyama, Junji, Riekel, Christian   +5 more
openaire   +2 more sources

Retention behavior of amino acids on plain, tri-n-butyl phosphate and tri-n-butylamine impregnated silica gel-G layers in mixed mobile phases

, 2002
Analytical Research Laboratory, Department of Chemistry, Hindu College, B-3, Jigar Colony, Moradabad-244 001, India Manuscript received 17 October 2001, revised 3 January 2002, accepted 23 April 2002 The retention behavior of twenty fouramino acids has been examined on plain, tri-n-butyl phosphate (TBP) and tri-n­-butylamine (TBA) impregnated silica ...
S. D. Sharma, Himanshu Sharma, Sumesh Chandra Sharma   +2 more
openaire   +2 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Reversed phase thin layer chromatography of amino acids on silicone fluid DC200, triaryl phosphate and tri-n-butylamine impregnated silica gel-G layers

, 2003
Analytical Research Laboratory, Department of Chemistry, Hindu College, B-3, Jigar Colony, Moradabad-244 001, India Manuscript received 6 September 2002, revised 11 February 2003, accepted 4 March 2003 Chromatographic behaviour of twentyfour amino acids has been studied on silicone fluid DC200, tiraryl phosphate (TAP) and tri-n-butylamine (TBA ...
S. D. Sharma, H. Sharma, C. Sharma
openaire   +1 more source