Results 101 to 110 of about 13,968,203 (346)
On transfer in bounded cohomology
, 2009 We define a transfer map in the setting of bounded cohomology with certain metric G-module coefficients. As an application, we extend a theorem of Chatterji, Mislin, Pittet and Saloff-Coste on the comparison map from Borel-bounded to Borel cohomology, to
Chatterji, Indira, Mislin, Guido
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
On Singular Localization of $\mathfrak{g}$-modules
, 2010 We prove a singular version of Beilinson-Bernstein localization for a complex semi-simple Lie algebra following ideas from the positive characteristic case done by \cite{BMR2}. We apply this theory to translation functors, singular blocks in the Bernstein-Gelfand-Gelfand category $\BGGcat$ and Whittaker modules.
Backelin, E, Kremnizer, K
openaire +3 more sources
The third cohomology group classifies crossed module extensions
, 2009 We give an elementary proof of the well-known fact that the third cohomology group H^3(G, M) of a group G with coefficients in an abelian G-module M is in bijection to the set Ext^2(G, M) of equivalence classes of crossed module extensions of G with M ...
Thomas, Sebastian
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Nature Communications, 2016 While the formation of myelin by oligodendrocytes is critical for the function of the central nervous system, the molecular mechanism controlling oligodendrocyte differentiation remains largely unknown.
Hyun-Jeong Yang +3 more
semanticscholar +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Nichols algebras of U_q(g)-modules
, 2004 A technique is developed to reduce the investigation of Nichols algebras of integrable U_q(g)-modules to the investigation of Nichols algebras of braided vector spaces with diagonal braiding. The results are applied to obtain information on the Gelfan'd-Kirillov dimension of these Nichols algebras and their defining relations if the braiding is of a ...
openaire +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
A rigid Leibniz algebra with non-trivial HL^2
, 2019 In this article, we generalize Richardson's example of a rigid Lie algebra with non-trivial $H^2$ to the Leibniz setting. Namely, we consider the hemisemidirect product ${\mathfrak h}$ of a semidirect product Lie algebra $M_k\rtimes{\mathfrak g}$ of a ...
Omirov, Bakhrom, Wagemann, Friedrich
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