Results 111 to 120 of about 13,968,203 (346)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
On Projective Fuzzy G –Modules
Souriar Sebastian, Thampy Abraham
openaire +1 more source
The quasi-Zariski topology-graph on the maximal spectrum of modules over commutative rings
Let M be a module over a commutative ring and let Max(M) be the collection of all maximal submodules of M. We topologize Max(M) with quasi-Zariski topology, where M is a Max-top module. For a subset T of Max(M), we introduce a new graph G(τT*m)$G(\tau_T^{
Ansari-Toroghy H., Habibi Sh.
doaj +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Categorification of Verma modules and indecomposable projective modules in the category $\mathcal I_{\mathfrak{g}}(\mathfrak{sl}_2)$ for $\mathfrak{sl}_2$ [PDF]
Ben Cox, Mee Seong Im
openalex +1 more source
Some Properties of Controlled K-g-Frames in Hilbert C∗-Modules
Rachid Echarghaoui +3 more
openalex +2 more sources
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Module amenability for Banach modules
We study the module amenability of Banach modules. This is a natural generalization of Johnson’s amenability of Banach algebras. As an example we show that for a discrete abelian group G, l p(G) is amenable as an l¹(G)-module if and only if G is amenable,
D Ebrahimi Bagha, M Amini
doaj
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source

