Results 181 to 190 of about 13,970,863 (343)

An Escherichia coli chromosomal "addiction module" regulated by guanosine [corrected] 3',5'-bispyrophosphate: a model for programmed bacterial cell death.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1996
E. Aizenman   +2 more
semanticscholar   +1 more source

Heteromeric guanosine (G)-quadruplex derived antenna modules with directional energy transfer [PDF]

open access: green, 2023
Mohammad Amin Zarandi   +7 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Automorphisms of Order 2p in Binary Self-Dual Extremal Codes of Length a Multiple of 24

open access: yesIEEE Transactions on Information Theory, 2013
Martino Borello, Wolfgang Willems
semanticscholar   +1 more source

Slice modules over minimal 2-fundamental algebras

open access: yesOpen Mathematics, 2007
Pogorzały Zygmunt, Szmyt Karolina
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Identification of a physiological E2 module for the human anaphase-promoting complex

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2009
Adam P Williamson   +5 more
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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