Results 11 to 20 of about 598,303 (159)

Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single-centre Australian experience. [PDF]

JPGN Rep
Abstract Objectives To evaluate the durability and predictors of loss of response of infliximab (IFX) over 2 years in paediatric Crohn's disease (CD) utilizing a proactive therapeutic drug monitoring (TDM) strategy. Methods A retrospective, single‐centre cohort study was conducted at The Children's Hospital at Westmead (CHW), Australia, from January ...
Chuah CW, Eldredge J, Magoffin A, O'Loughlin EV, Park CJ, Puppi J, Siew S, Stormon M, Thacker K, Dutt S.   +9 more
europepmc   +2 more sources

Modulation of Anaphase-Promoting Complex Genes Regulates Root-Knot Nematode Gall Development and Plant Susceptibility. [PDF]

Plant Cell Environ
ABSTRACT The anaphase‐promoting complex/cyclosome (APC/C) is a multi‐subunit E3 ubiquitin ligase that regulates cell cycle progression, but its role in plant‐pathogen interactions is poorly understood. Here, we demonstrate that regulation of the ubiquitin–proteasome system, involving APC/C‐associated components, is critical for coordinating host cell ...
Carneiro AK, Siqueira KMS, Anh H, Pagnotta S, Nascimento DCD, Eloy NB, Keller H, Hemerly AS, Engler JA.   +8 more
europepmc   +2 more sources

The Effect of Adding Terminalia chebula Powder to Broilers Subjected to Salmonella spp. on Performance, Immunity, Lipid Profile and Histology. [PDF]

Vet Med Sci
The study goal was to evaluate the effects of adding Terminalia chebula powder on the performance, immune response and histological health of broilers challenged with Salmonella spp. Terminalia chebula with 750 mg/kg significantly improved body weight, feed intake, lipid profiles and alleviated the negative effects of the Salmonella challenge. ABSTRACT
Hamood MF, Abdaljaleel RA, Alsadwi AM.
europepmc   +2 more sources

Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest [PDF]

, 2015
TGFbeta is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity.
Dunbar, Donald R, Harrison, David J, Sheahan, Sharon, Bellamy, Christopher O, Prost, Sandrine   +4 more
core   +4 more sources

Safety evaluation of the food enzyme aspergillopepsin I from the non-genetically modified <i>Aspergillus</i> sp. strain LPL 3U-3-10. [PDF]

EFSA J
Abstract The food enzyme aspergillopepsin I (EC 3.4.23.18) is produced with the non‐genetically modified Aspergillus sp. strain LPL 3U‐3‐10 by Shin Nihon Chemical Co., Ltd. The food enzyme was considered free from viable cells of the production organism. It is intended to be used in 16 food manufacturing processes. Since residual amounts of food enzyme–
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Andreoli C, Terron A, Yurkov A, Cavanna D, Aguilera J, Peluso S, Andryszkiewicz M, Kovalkovicova N, Liu Y.   +21 more
europepmc   +2 more sources

The Fission Yeast Homeodomain Protein Yox1p Binds to MBF and Confines MBF-Dependent Cell-Cycle Transcription to G1-S via Negative Feedback [PDF]

, 2009
The regulation of the G1- to S-phase transition is critical for cell-cycle progression. This transition is driven by a transient transcriptional wave regulated by transcription factor complexes termed MBF/SBF in yeast and E2F-DP in mammals. Here we apply
Brazma Alvis, Klier, S, Codlin, S, Lackner Daniel H., Bahler, J, Alvis Brazma, Brian T Wilhelm, Robertus A M de Bruin, Sofia Aligianni, de Bruin, RAM, Daniel H Lackner, Sandra Codlin, Gabriella Rustici, Klier Steffi, Wilhelm, BT, Rustici Gabriella, Lackner, DH, Marguerat Samuel, Aligianni, S, Bähler Jürg, de Bruin, RA, Jürg Bähler, Brazma, A, Codlin Sandra, Marguerat, S, Steffi Klier, Wilhelm Brian T., Samuel Marguerat, Aligianni Sofia, de Bruin Robertus A. M., Rustici, G   +30 more
core   +1 more source

GEOGRAPHIC INFORMATION SYSTEM OF THE DIOCESE OF GEORGIA

InterCarto. InterGIS, 2016
GIS of Georgian eparchies is cartographic – GIS product which includes systematized information about Georgian boundary changes in 1920-2002, which is presented with dynamic items on the map. Conditions of Georgian episcopal eparchies in XVIII century by
T. P. Gordeziani, Z. D. Laoshvili, T. I. Donadze, M. D. Sharashenidze, R. Sh. Tolordava   +4 more
doaj   +1 more source

MAPPING OF MEMORIAL TREES OF HOLY PLACES IN RUSSIA AND THE NEAR ABROAD

InterCarto. InterGIS, 2013
The history of the Orthodox Church in Russia and the Near Abroad is related by definite mode with world of nature environment. Trees growing now or existed in the past in territories of holy places are elements of this world.
O. I. Kotova
doaj   +1 more source

G1-S_SYSBIO.IT_Model v1.0

, 2016
The model focuses on the core mechanism of cell size control in steady state growth, no consideration being given yet on how changes in nutrients or growth rate affect cell size.
SYSBIO-IT
core   +1 more source

Analysis of geomagnetic data obtained at multi observatories near Syowa Station during the IMS (1976-1978)-Correlation of the location of auroral electrojet current with the aurora and the behavior of geomagnetic conjugacy -

Antarctic Record, 1998
This report describes the movement of small scale auroral electrojet current regions and their relationships to spatial and temporal variation of visual auroras based on magnetic data at three ground stations [Syowa (69°00′S, 39°36′E, 30m a. s.
Masaru Ayukawa, Kazuo Makita
doaj   +1 more source