Results 11 to 20 of about 242,491 (158)

Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single-centre Australian experience. [PDF]

JPGN Rep
Abstract Objectives To evaluate the durability and predictors of loss of response of infliximab (IFX) over 2 years in paediatric Crohn's disease (CD) utilizing a proactive therapeutic drug monitoring (TDM) strategy. Methods A retrospective, single‐centre cohort study was conducted at The Children's Hospital at Westmead (CHW), Australia, from January ...
Chuah CW, Eldredge J, Magoffin A, O'Loughlin EV, Park CJ, Puppi J, Siew S, Stormon M, Thacker K, Dutt S.   +9 more
europepmc   +2 more sources

The Impact of Genotoxicity in Coke Oven Workers: Systematic Review With Meta-Analysis. [PDF]

J Appl Toxicol
ABSTRACT This systematic review (SR) with meta‐analysis investigates the genotoxicity potential of coke oven workers (COWs) exposed to polycyclic aromatic hydrocarbons (PAHs) through a comprehensive analysis of studies retrieved from PubMed, SCOPUS, and Web of Science.
Pinto TG, do Nascimento VF, Guerra GAH, Takeshita WM, Sales RA, de Moraes Malinverni AC, Guimaraes LL, Ribeiro DA.   +7 more
europepmc   +2 more sources

Safety evaluation of the food enzyme pectin lyase from the non-genetically modified <i>Aspergillus luchuensis</i> strain CBS 141530. [PDF]

EFSA J
Abstract The food enzyme pectin lyase (1,4‐6‐O‐methyl‐α‐D‐galacturonan lyase; EC 4.2.2.10) is produced with the non‐genetically modified Aspergillus luchuensis strain CBS 141530 by Solyve. The food enzyme was considered free from viable cells of the production organism. It is intended to be used in 12 food manufacturing processes.
EFSA Panel on Food Enzymes (FEZ), Zorn H, Baviera JMB, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Andreoli C, Terron A, Yurkov A, Andryszkiewicz M, Cavanna D, Kovalkovicova N, Liu Y.   +19 more
europepmc   +2 more sources

Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest [PDF]

, 2015
TGFbeta is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity.
Dunbar, Donald R, Harrison, David J, Sheahan, Sharon, Bellamy, Christopher O, Prost, Sandrine   +4 more
core   +4 more sources

The Fission Yeast Homeodomain Protein Yox1p Binds to MBF and Confines MBF-Dependent Cell-Cycle Transcription to G1-S via Negative Feedback [PDF]

, 2009
The regulation of the G1- to S-phase transition is critical for cell-cycle progression. This transition is driven by a transient transcriptional wave regulated by transcription factor complexes termed MBF/SBF in yeast and E2F-DP in mammals. Here we apply
Brazma Alvis, Klier, S, Codlin, S, Lackner Daniel H., Bahler, J, Alvis Brazma, Brian T Wilhelm, Robertus A M de Bruin, Sofia Aligianni, de Bruin, RAM, Daniel H Lackner, Sandra Codlin, Gabriella Rustici, Klier Steffi, Wilhelm, BT, Rustici Gabriella, Lackner, DH, Marguerat Samuel, Aligianni, S, Bähler Jürg, de Bruin, RA, Jürg Bähler, Brazma, A, Codlin Sandra, Marguerat, S, Steffi Klier, Wilhelm Brian T., Samuel Marguerat, Aligianni Sofia, de Bruin Robertus A. M., Rustici, G   +30 more
core   +1 more source

Safety evaluation of the food enzyme endo-polygalacturonase from the non-genetically modified <i>Aspergillus tubingensis</i> strain SPG 10-1199. [PDF]

EFSA J
Abstract The food enzyme endo‐polygalacturonase (1,4‐α‐d‐galacturonan glycanohydrolase; EC 3.2.1.15) is produced with the non‐genetically modified Aspergillus tubingensis strain SPG 10‐1199 by Shin Nihon Chemical Co., Ltd. The food enzyme was considered free from viable cells of the production organism.
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Andreoli C, Terron A, Peluso S, Cavanna D, Andryszkiewicz M, Criado A, Liu Y.   +19 more
europepmc   +2 more sources

GEOGRAPHIC INFORMATION SYSTEM OF THE DIOCESE OF GEORGIA

InterCarto. InterGIS, 2016
GIS of Georgian eparchies is cartographic – GIS product which includes systematized information about Georgian boundary changes in 1920-2002, which is presented with dynamic items on the map. Conditions of Georgian episcopal eparchies in XVIII century by
T. P. Gordeziani, Z. D. Laoshvili, T. I. Donadze, M. D. Sharashenidze, R. Sh. Tolordava   +4 more
doaj   +1 more source

MAPPING OF MEMORIAL TREES OF HOLY PLACES IN RUSSIA AND THE NEAR ABROAD

InterCarto. InterGIS, 2013
The history of the Orthodox Church in Russia and the Near Abroad is related by definite mode with world of nature environment. Trees growing now or existed in the past in territories of holy places are elements of this world.
O. I. Kotova
doaj   +1 more source

Safety evaluation of the food enzyme containing endo-polygalacturonase and pectinesterase activities from the non-genetically modified <i>Aspergillus luchuensis</i> strain AP2 903-6. [PDF]

EFSA J
Abstract The food enzyme containing endo‐polygalacturonase (1,4‐α‐d‐galacturonan glycanohydrolase; EC 3.2.1.15) and pectinesterase (pectin pectylhydrolase; EC 3.1.1.11) activities is produced with the non‐genetically modified Aspergillus luchuensis strain AP2 903‐6 by Shin Nihon Chemical Co. Ltd. The food enzyme was considered free from viable cells of
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Andreoli C, Terron A, Yurkov A, Aguilera J, Andryszkiewicz M, Cavanna D, Criado A, Liu Y.   +20 more
europepmc   +2 more sources

Analysis of geomagnetic data obtained at multi observatories near Syowa Station during the IMS (1976-1978)-Correlation of the location of auroral electrojet current with the aurora and the behavior of geomagnetic conjugacy -

Antarctic Record, 1998
This report describes the movement of small scale auroral electrojet current regions and their relationships to spatial and temporal variation of visual auroras based on magnetic data at three ground stations [Syowa (69°00′S, 39°36′E, 30m a. s.
Masaru Ayukawa, Kazuo Makita
doaj   +1 more source