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Dynamic Bolting Analysis of Centerstack Casing G10 Ring for NSTX-U
Fusion Science and Technology, 2021Jiarong Fang, P Titus
exaly
Targeting KRAS G12D and G10 Mutations with Novel Small Molecule Inhibitors
ACS Medicinal Chemistry LettersKRAS mutations, particularly G12D and G10, drive oncogenesis in multiple cancers. Recent patents WO 2025/054347 A1 and WO 2025/054530 A1 disclose novel small molecule inhibitors that selectively target these mutations, demonstrating high potency, favorable pharmacokinetics, and promising therapeutic potential in challenging pancreatic, lung, and ...
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