Results 201 to 210 of about 132,339 (282)

Correction: The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos Syndrome. [PDF]

open access: yesCell Death Discov
Omar R   +13 more
europepmc   +1 more source

Tropical fishes can benefit more from novel than familiar species interactions at their cold‐range edges

open access: yesJournal of Animal Ecology, Volume 94, Issue 10, Page 1997-2010, October 2025.
We reveal that shoaling with temperate fish enhances foraging efficiency in range‐extending tropical fish species, suggesting novel species interactions can aid poleward expansions in marine ecosystems. Our work highlights behavioural plasticity as a mechanism that can facilitate tropical fishes to adapt to novel temperate ecosystems under climate ...
Angus Mitchell   +4 more
wiley   +1 more source

KYNA Ameliorates Hepatic Ischemia–Reperfusion Injury by Activating the Hippo Signalling Pathway via FTO‐Dependent m6A Demethylation of LATS1

open access: yesCell Proliferation, Volume 58, Issue 10, October 2025.
Our study elucidates the cellular and molecular mechanisms underlying KYNA's protective effects against HIRI. It emphasises that KYNA modulates the methylation status of the Hippo signalling pathway through the activation of AHR, thereby mitigating damage by promoting LATS1 degradation and facilitating the nuclear translocation of YAP. ABSTRACT Hepatic
Wenjie Zheng   +10 more
wiley   +1 more source

Gαs‐specific structural elements attenuate interactions with regulator of G protein signaling (RGS) proteins

open access: yesThe FEBS Journal, Volume 292, Issue 19, Page 5244-5254, October 2025.
Heterotrimeric (αβγ) G proteins are usually inactivated by regulators of G protein signaling (RGS) proteins, but Gαs is an exception. Comparative structural analysis identified unique Gαs structural elements that may interfere with RGS binding. Mutagenesis and biochemical assays showed that three residues in the Gαs GTPase domain are both necessary and
Sabreen Higazy‐Mreih   +4 more
wiley   +1 more source

Exercise electrocardiography stress testing in suspected angina and non-obstructive coronary arteries. [PDF]

open access: yesEur Heart J
Sykes R   +15 more
europepmc   +1 more source

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