Results 181 to 190 of about 1,157,795 (274)

Comparative efficacy and safety of antiresorptive and anabolic therapies for male osteoporosis: an updated Bayesian network meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Li Z, Zhang L, Xue C, Lu C, Wang L.
europepmc   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

D1 in G2 [PDF]

Cell Cycle, 2002
openaire   +3 more sources

Well-Differentiated Neuroendocrine Tumors of Lung: A Case Series Supporting the IARC/WHO Common Classification of Neuroendocrine Tumor Nomenclature and Grading. [PDF]

Endocr Pathol
Altun E, Savari O, Maravillas MA, Asa SL.   +3 more
europepmc   +1 more source

Single‐Atom Pt Anchoring on Self‐Doped ZrO2@G‐C3N4 Nanostructure Enables Efficient Photocatalytic Seawater Hydrogen Evolution

Advanced Science, EarlyView.
Grain‐like Zr3+‐ZrO2 and Pt single atoms are integrated into an S‐scheme Zr3+‐ZrO2@g‐C3N4 heterostructure to enable efficient visible‐light‐driven seawater hydrogen production. The combined effect of Pt single‐atom sites and the S‐scheme charge‐transfer pathway accelerates carrier separation, preserves strong redox ability, and markedly enhances ...
Hezheng Sun, Yifan Guo, Xin Yu, Yajie Tian, Feng Gao, Bin Wang, Yanting Tang, Dani S. Assi, Vellaisamy A. L. Roy   +8 more
wiley   +1 more source

Effect of the Design and Exposure Mode of Different Multiple-Peak Light-Curing Units on Light Emission, Temperature Rise, and Intraoral Access. [PDF]

J Adhes Dent
Ribeiro MTH, Benoni GM, Lozada MIT, Rondon AKA, da Silva GR, Soares CJ.   +5 more
europepmc   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Orderly mitosis shapes interphase genome architecture. [PDF]

Elife
Guin K, Keikhosravi A, Chari R, Pegoraro G, Misteli T.   +4 more
europepmc   +1 more source

G2 Phase

Reactome - a curated knowledgebase of biological pathways, 2003
M O'Connell, N Walworth
openaire   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source