Results 151 to 160 of about 123,954 (243)

Miniaturized Droplet‐Based Adaptation of the Ames Test for High‐Throughput Mutagenicity Assessment

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This work presents the first demonstration of a tube‐based droplet microfluidic implementation of the Ames test, bridging single‐droplet resolution with regulatory genotoxicity testing. The Ames test is a cornerstone assay for detecting mutagenicity, but conventional plate‐ and well‐based formats suffer from high reagent consumption, low ...
Jialan Cao   +3 more
wiley   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol   +4 more
wiley   +1 more source

[B6, G3] Détente...

open access: yesLe ciné-œil numérique, 2013
openaire   +1 more source

Intergenerational transmission of anxiety: A comparison of transdiagnostic and disorder‐specific pathways

open access: yesJCPP Advances, EarlyView.
Abstract Background Individuals with a parental history of anxiety disorders are at risk of developing an anxiety disorder. Prior studies have focused on the transmission of specific anxiety disorders across generations (i.e., disorder‐specific transmission), often overlooking the possibility that a general tendency to develop various forms of anxiety ...
Hyunsik Kim   +5 more
wiley   +1 more source

Engineering Enantiocomplementary Protoglobins for Stereoconvergent Construction of <i>N</i>-Alkylated α-Aminoketones. [PDF]

open access: yesJ Am Chem Soc
Qin ZY   +8 more
europepmc   +1 more source

Projected Intensification of Hydroclimatic Extremes in Rio Grande do Norte, Brazil, Under CMIP6 Scenarios

open access: yesInternational Journal of Climatology, EarlyView.
The graphical abstract presents observed (1963–2023) and projected changes in hydroclimatic extremes in Rio Grande do Norte, Brazil. It integrates dry‐spell duration (CDD) and extreme precipitation (R95pTOT) using CMIP6 multimodel ensembles under SSP1‐2.6, SSP2‐4.5, and SSP5‐8.5.
Daris Correia dos Santos
wiley   +1 more source

Targeting SRC enhances differentiation and promotes multifaceted cell death mechanisms in recurrent group 3 medulloblastoma. [PDF]

open access: yesCell Death Dis
Kuzmychova H   +11 more
europepmc   +1 more source

G3 2023 Reviewer Index

open access: yesG3: Genes, Genomes, Genetics, 2023
openaire   +1 more source

What Do Latest CMIP6 Global Climate Models Say About Future Arctic Sea Ice Coverage Changes?

open access: yesInternational Journal of Climatology, EarlyView.
Modelling of sea ice dynamics has significantly improved between CMIP5 and CMIP6, with nearly three times as many models capturing realistic annual variability in sea ice extent (SIE). What we previously thought was a non‐linear pattern of low SIE observations in 2007–2010 that would continue throughout time now appears to be non‐record‐setting lows in
Jessica L. Matthews   +4 more
wiley   +1 more source

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