Results 51 to 60 of about 6,050 (175)
Cortisol Recognition by a Conformationally Responsive DNA Aptamer
The full‐length 85mer cortisol aptamer intrinsically populates two metastable conformational states in equilibrium. Cortisol binding redistributes the conformational ensemble by shifting the equilibrium between open and compact states while maintaining the underlying secondary structure. This ligand‐induced tertiary reorganization provides an atomistic
Lakshitha Jasin Arachchige +4 more
wiley +1 more source
At its 19th National Congress, the Communist Party of China vowed to “strengthen the financial sector’s ability to serve the real economy.” However, many studies provide evidence of the opposite trend, a problematic “transition from the real to the ...
Dapeng Tang, Jiamei Wu, Zhibin Chen
doaj +1 more source
Abstract INTRODUCTION Obesity may increase Alzheimer's disease (AD) risk, yet the underlying mechanisms remain unclear. METHODS We investigated this link through global epidemiology, Mendelian randomization (MR), transcriptomics, clinical cohort validation, and mechanistic exploration.
Xiaohang Qian +9 more
wiley +1 more source
National Governance Quality, Competition and Firm Investment
This study investigates how market competition affects firm investment and the moderating effect of national governance quality (CGI) on the relationship between competition and firm investment in research and development (R&D) and tangible assets.
Phan Quynh Trang, Nguyen Van Diep
doaj +1 more source
ABSTRACT Cardiovascular risk factors are often undertreated in patients with dementia. Renin‐angiotensin system inhibitors (RASI) are first‐line treatments for hypertension. We examined the association between RASI and all‐cause mortality in hypertensive patients with and without dementia, comparing angiotensin‐converting enzyme inhibitors (ACEI) to ...
Marta Villa Lopez +14 more
wiley +1 more source
Учебная дисциплина «Высшая математика» относится к физикоматематическому модулю государственного компонента. Учебная программа составлена на основе типовой программы ТД-G 471/тип от 10.03.2014, типовых учебных планов №G31-1-016/пр-тип., №G31-1-017/пр ...
Коваленко, Николай Семенович +2 more
core
Abstract Intergroup contact reduces prejudice, but its potential to foster broader personal and societal change remains understudied. We address these gaps by examining a large‐scale peacebuilding intervention (PEACE4Youth) among marginalized youth in post‐conflict Northern Ireland.
Danielle L. Blaylock +6 more
wiley +1 more source
Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao +10 more
wiley +1 more source

