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Two Lineages of DS-1-Like G3P[8] Human Rotaviruses in Sabah, Malaysia: Genetic Diversity and Evidence of Reassortment. [PDF]

open access: yesJ Med Virol
ABSTRACT Group A rotavirus (RVA) genotype G3P[8] strains typically carry a Wa‐like genomic backbone, but DS‐1‐like G3P[8] reassortants have disseminated globally since 2013. In Sabah, Malaysia, surveillance in 2018–2019 identified frequent G3P[8] strains with a short RNA electropherotype, consistent with DS‐1‐like backbones.
Akari Y   +11 more
europepmc   +2 more sources

Molecular Characterization of Rotavirus From Under-Five Children Presenting With Diarrhea at a Tertiary Hospital in Northeast Nigeria. [PDF]

open access: yesInt J Pediatr
Background Diarrhea is a leading cause of morbidity and mortality among children in developing countries. Rotavirus is a significant cause of acute watery diarrhea in children under 5 years of age, which can be fatal. This study is aimed at investigating the prevalence of rotavirus gastroenteritis (RVGE) in children and characterizing the prevalent ...
Ali KB   +11 more
europepmc   +2 more sources

Emergence of equine‐like G3 and porcine‐like G9 rotavirus strains in Sarawak, Malaysia: 2019−2021

open access: yesJournal of Medical Virology, Volume 95, Issue 8, August 2023., 2023
Abstract Rotavirus is the leading causative viral agent of pediatric acute gastroenteritis globally, infecting mostly children 5 years old and below. Data on rotavirus prevalence in Malaysia is scarce, despite the WHO's recommendation for continuous rotavirus surveillance, and has underestimated the need for national rotavirus vaccination ...
Ahmad Syatir Tahar   +7 more
wiley   +1 more source

Molecular epidemiology of rotavirus among children in Western Canada: Dynamic changes in genotype prevalence in four consecutive seasons

open access: yesJournal of Medical Virology, Volume 95, Issue 8, August 2023., 2023
Abstract Rotavirus molecular surveillance remains important in the postvaccine era to monitor the changes in transmission patterns, identify vaccine‐induced antigenic changes and discover potentially pathogenic vaccine‐related strains. The Canadian province of Alberta introduced rotavirus vaccination into its provincial vaccination schedule in June ...
Ran Zhuo   +12 more
wiley   +1 more source

Genetic diversity of rotavirus strains circulating in Norway before and after the introduction of rotavirus vaccination in children

open access: yesJournal of Medical Virology, Volume 94, Issue 6, Page 2624-2631, June 2022., 2022
Abstract Globally, rotavirus (RV) is the leading cause of acute gastroenteritis (AGE) in young children under 5 years of age. Implementation of RV vaccination is expected to result in fewer cases of RV in the target population, but it is unknown if this also results in vaccine‐induced virus strain replacement. Rotarix, a monovalent vaccine based on G1P[
Moustafa Gibory   +10 more
wiley   +1 more source

Global and Swedish review of rotavirus vaccines showed considerable reductions in morbidity and mortality

open access: yesActa Paediatrica, Volume 110, Issue 12, Page 3161-3169, December 2021., 2021
Abstract Rotavirus infections cause severe gastroenteritis in small children, with both high morbidity and mortality. The rotavirus vaccine has been recommended by the World Health Organization since 2009 and was being used by 108 countries by 2019. It joined Sweden's national immunisation programme that year, after 5 years of selective regional use ...
Lina Schollin Ask
wiley   +1 more source

Rotavirus in Calves and Its Zoonotic Importance

open access: yesVeterinary Medicine International, Volume 2021, Issue 1, 2021., 2021
Rotavirus is a major pathogen responsible for diarrheal disease in calves, resulting in loss of productivity and economy of farmers. However, various facets of diarrheal disease caused by rotavirus in calves in the world are inadequately understood, considering that diarrheal disease caused by rotavirus is a vital health problem in calves that ...
Umer Seid Geletu   +3 more
wiley   +1 more source

Effect of rotavirus vaccine implementation on the prevalence of coinfections with enteric viruses in Norway

open access: yesJournal of Medical Virology, Volume 92, Issue 12, Page 3151-3156, December 2020., 2020
Abstract Acute gastroenteritis (AGE) is a common illness in both adults and children worldwide and is caused by several microorganisms including viruses, bacteria, and parasites. Rotavirus (RV), which is the main cause of AGE, can occur as a mixed infection with other viruses.
Moustafa Gibory   +4 more
wiley   +1 more source

Supercharged Proteins and Polypeptides

open access: yesAdvanced Materials, Volume 32, Issue 20, May 22, 2020., 2020
Natural proteins with high net charges can be an inspiration for scientists to artificially supercharge other protein entities. Recent findings show that supercharging proteins allows for control of their properties such as temperature resistance and catalytic activity.
Chao Ma   +4 more
wiley   +1 more source

Recent Increase in Rotavirus Gastroenteritis After Five Years of Low Activity in Hokkaido Prefecture, Japan, Associated With Equine‐Like G3P[8] and G8P[8] Strains, 2025

open access: yesJournal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Rotavirus gastroenteritis decreased substantially worldwide during the COVID‐19 pandemic, and activity remained minimal in Hokkaido Prefecture, Japan, for 5 years after 2020. Hospital‐based surveillance in Hokkaido since July 2019 identified the first resurgence of rotavirus gastroenteritis in 2025.
Yuya Fukuda   +20 more
wiley   +1 more source

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