Results 121 to 130 of about 14,189,076 (192)
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Louis K. Kiddgett telegram to Warren G. Harding, August 28, 1920
In this telegram dated August 28, 1920, Louis K. Kiddgett, president of the Republican League of Massachusetts, writes to Senator Warren G. Harding to share that 15,000 men and women met for the group's first meeting in full support of Harding's ...
Kiddgett, Louis K.
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
F. Edward Mitchell telegram to Warren G. Harding, August 28, 1920
Dated August 28, 1920, this telegram from F. Edward Mitchell to Senator Warren G. Harding states that 200 former Democrats formed the Harding Democratic Club of the District of Columbia, based on the principle that Americanism opposes Internationalism ...
Mitchell, F. Edward
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Commento agli artt. 28-40 della legge 22 aprile 2005 n. 69 sul mandato d'arresto europeo
L'autore esamina gli artt. da 28 a 40 della legge 22 aprile 2005 sul mandato d'arresto europeo delineando le posizioni della giurisprudenza e della ...
COLAIACOVO G
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
G. E. Lessing's gesammelte Werke.
G. E. LESSING'S GESAMMELTE WERKE. G. E. Lessing's gesammelte Werke. Nathan der Weise. (1854) ( -
Lessing, Gotthold Ephraim +1 more
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Ralph W. Tyler letter to Warren G. Harding, January 28, 1920
In this letter dated January 28, 1920, Managing Editor of The Cleveland Advocate Ralph Tyler writes to Senator Warren G. Harding to ask that he write to his colleagues in the Ohio General Assembly to initiate a bill that would transfer state control of ...
Tyler, Ralph W., 1860-1921
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source

