Results 81 to 90 of about 14,189,076 (192)
Letter - Sean O'Sullivan to John G. Doherty, 28 April 1975
, 2015 A letter from Sean O'Sullivan to John G. Doherty, editor of The Spectator, 28 April 1975. The letter includes comments from O'Sullivan regarding the direction of the Progressive Conservative ...
Doherty, John G.
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Field testing and dynamic analysis of old continuous truss steel bridge
The Baltic Journal of Road and Bridge Engineering, 2018 Paper presents dynamic field test and analysis results of a three span railway steel continuous truss bridge over river Neris in Jonava. Bridge was originally constructed in 1914.
Artūras Kilikevičius +6 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Warren G. Harding letter to Harry M. Daugherty, October 28, 1919
, 1919 In this letter dated October 28, 1919, Senator Warren Harding writes to his campaign manager Harry Daugherty in response to his letter of October 24, stating that he met with the Republican Committee in regards to relinquishing his role as senator after ...
Harding, Warren G. (Warren Gamaliel), 1865-1923
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Oral history interview with Participant 28
, 2018 Participant 28 discusses their experience using the Our Daily Bread food resource center. They share some of their concerns with the center such as allowing school-age volunteers which prevents them from bringing their grandchild during the week for fear
Participant 28
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