Results 81 to 90 of about 46,898 (102)

Editorial

open access: yesKartografija i Geoinformacije, 2008
Miljenko Lapaine
doaj  

Role of Calcium Signaling in GA101-Induced Cell Death in Malignant Human B Cells [PDF]

open access: yesCancers, 2019
International audienceGA101/obinutuzumab is a novel type II anti-CD20 monoclonal antibody (mAb), which is more effective than rituximab (RTX) in preclinical and clinical studies when used in combination with chemotherapy.
Simon Latour   +2 more
exaly   +2 more sources

Preclinical Studies on the Mechanism of Action and the Anti-Lymphoma Activity of the Novel Anti-CD20 Antibody GA101

open access: yesMolecular Cancer Therapeutics, 2011
International audienceGA101 is a novel glycoengineered Type II CD20 monoclonal antibody. When compared with rituximab, it mediates less complement-dependent cytotoxicity (CDC).
Lina Reslan   +2 more
exaly   +2 more sources

Unexpected cross-reactivity of anti-cathepsin B antibodies leads to uncertainties regarding the mechanism of action of anti-CD20 monoclonal antibody GA101 [PDF]

open access: yesLeukemia Research, 2017
International audienceGA101, also known as obinutuzumab or Gazyva (Gazyvaro), is a glycoengineered type II humanized antibody that targets the CD20 antigen expressed at the surface of B-cells.
Jérôme Kucharczak   +2 more
exaly   +2 more sources

Obinutuzumab (GA101) Monotherapy in Relapsed/Refractory Diffuse Large B-Cell Lymphoma or Mantle-Cell Lymphoma: Results From the Phase II GAUGUIN Study

open access: yesJournal of Clinical Oncology, 2013
International audiencePurposeObinutuzumab (GA101), a type II, glycoengineered, humanized anti-CD20 monoclonal antibody, was superior to rituximab in human diffuse large B-cell lymphoma (DLBCL) and mantle-cell lymphoma (MCL) xenograft models.
Guillaume Cartron   +2 more
exaly   +2 more sources
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Comparison of the in vitro effects of the anti‐CD20 antibodies rituximab and GA101 on chronic lymphocytic leukaemia cells

British Journal of Haematology, 2011
Lukas P Frenzel   +2 more
exaly  

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