Results 121 to 130 of about 4,103 (198)

α‐Synuclein strain homogeneity in multiple system atrophy subtypes

open access: yesBrain Pathology, EarlyView.
Two different subtypes of multiple system atrophy are recognized: MSA‐C and MSA‐P. In this manuscript, Lau et al. investigate whether MSA‐C and MSA‐P are caused by different strains of α‐synuclein aggregates. By performing conformational fingerprinting experiments as well as in vitro and in vivo seeding assays, their findings suggest that both MSA‐C ...
Heather H. C. Lau   +10 more
wiley   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

open access: yesBrain Pathology, EarlyView.
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar   +12 more
wiley   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

open access: yesBritish Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Understanding Rheumatoid Arthritis‐Oral Health Perceptions Around Diagnosis and the Early Disease Course: A Phenomenological Approach

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To explore how Dutch adults with rheumatoid arthritis (RA) perceive their oral health around the diagnostic process and the early disease course. The primary objective was to describe these perceptions in depth, and a secondary objective was to identify areas for future patient‐centred research.
Nadine Isabel Bhagwandas   +2 more
wiley   +1 more source

Real‐time by‐example texture synthesis and filtering using local statistics exchange

open access: yesComputer Graphics Forum, EarlyView.
Abstract Real‐time by‐example texture synthesis is used in interactive virtual worlds to generate the appearance of an unbounded surface from an exemplar texture with as few repetitions as possible. Currently, leading real‐time methods rely on a tiling and blending scheme which is known to synthesize well texture patterns with little spatial ...
Nicolas Lutz, Guillaume Gilet
wiley   +1 more source

NAADF: Globally Illuminated Voxel Worlds Accelerated with Nested Axis‐Aligned Distance Fields

open access: yesComputer Graphics Forum, EarlyView.
Abstract Achieving realistic rendering of 3D scenes in real time using path tracing is challenging due to the high sample count required, with ray tracing as the bottleneck. Focusing on voxels as a geometry representation offers significant opportunities for optimizations, especially for tracing the rays, but also for computing the samples.
A. Ulschmid   +4 more
wiley   +1 more source

Evaluating the Perceptual Space of Surface Noise for Visualization

open access: yesComputer Graphics Forum, EarlyView.
Abstract Surface noise provides a geometric alternative to color for encoding scalar information on surfaces, yet its perceptual characteristics remain insufficiently understood. We present a systematic investigation of how variations in noise amplitude and frequency are perceived when applied to 3D surfaces. Across three online perceptual studies with
A. Sterzik, N. Merk, K. Lawonn
wiley   +1 more source

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