Results 41 to 50 of about 136,130 (308)

A gadolinium cryptate with two coordinated water molecules

open access: yes, 1998
An X-ray crystallographic structure determination of the nitrate salt of the gadolinium imBT cryptate shows coordination of two water molecules; NMRD relaxometry of this cryptate reveals a relaxivity of 5.8 mM–1 s–1 (at 10 MHz, 298 K and pH 6), which is ...
Drew, M.G.B.   +4 more
core   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

Design of Wood-Based Gd (III)-Hemoporphyrin Monomethyl Ether Eco-Material for Optical Oxygen Sensing with a Wide Detection Range

open access: yesSensors
Gaseous oxygen detection is essential in numerous production and manufacturing sectors. To meet the varying oxygen detection requirements across different fields, techniques that offer a wide oxygen detection range should be developed.
Yujie Niu   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio
Mechanically activated (MA) Piezo1 channels play an important role in both normal physiology and pathological dysfunction in multiple tissues and organs. In skeletal muscle cells, Piezo1 channels are involved in the regulation of postnatal myogenesis and
Natalia A. Vilchinskaya   +3 more
doaj   +1 more source

Wide Range Mechanical Customization of Mg-Gd Alloys With Low Degradation Rates by Extrusion

open access: yesFrontiers in Materials, 2019
Currently, only a few magnesium alloys have been approved for implant applications. For biomedical purposes, the choice of the alloying elements is a critical parameter and rare earth elements have been proven to be mechanically suitable and biologically
Jochen Harmuth   +4 more
doaj   +1 more source

Synthesis and studies of gadolinium texaphyrin conjugates and model platinum therapeutic agents [PDF]

open access: yes, 2008
textThe experimental cancer therapeutic agent gadolinium texaphyrin (MGd) is a cationic paramagnetic expanded porphyrin currently being tested as an X-Ray sensitizing (XRS) agent, and is a compound with demonstrated tumor localization.
Fountain, Mark Edward, 1960-
core  

Delayed reaction following gadolinium-based contrast agent application. [PDF]

open access: yes, 2018
Both iodinated contrast media and gadolinium-based contrast agents (GBCAs) can induce immediate hypersensitivity reactions. In addition, iodinated contrast media have been shown to be responsible for delayed or non-immediate reactions that occur 1 h up ...
Johannes T. Heverhagen   +3 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Evaluating Magnetocaloric Effect in Magnetocaloric Materials: A Novel Approach Based on Indirect Measurements Using Artificial Neural Networks

open access: yesEnergies, 2019
The thermodynamic characterisation of magnetocaloric materials is an essential task when evaluating the performance of a cooling process based on the magnetocaloric effect and its application in a magnetic refrigeration cycle.
Angelo Maiorino   +5 more
doaj   +1 more source

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