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Gadolinium toxicity and treatment [PDF]
Magnetic Resonance Imaging, 2016 AbstractGadolinium based contrast agents (GBCAs) play an important role in the diagnostic evaluation of many patients. The safety of these agents has been once again questioned after gadolinium deposits were observed and measured in brain and bone of patients with normal renal function.
Richard Semelka +2 more
exaly +6 more sources
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Journal of Nanoscience and Nanotechnology, 2021
Fullerenes—A new combining atoms of carbon atoms into the molecule, which can serve as the parent and precursor of a whole class advanced organic compounds. Unsolved problems associated with a correct understanding of the structure, transformation, and behavior of the fullerene C60 molecule, make it impossible to interpret correctly many of its ...
Nazym Yerlanovna, Akhanova +8 more
openaire +2 more sources
Fullerenes—A new combining atoms of carbon atoms into the molecule, which can serve as the parent and precursor of a whole class advanced organic compounds. Unsolved problems associated with a correct understanding of the structure, transformation, and behavior of the fullerene C60 molecule, make it impossible to interpret correctly many of its ...
Nazym Yerlanovna, Akhanova +8 more
openaire +2 more sources
Hysterosalpingography with gadolinium
European Radiology, 2004We report a case of diagnostic hysterosalpingography performed using gadoteric acid (1,350 mOsm) in a patient with a prior severe generalized adverse reaction to iodinated contrast media.
DE CARO, GIOVANNI +4 more
openaire +3 more sources
Gadolinium deposition in the brain
Magnetic Resonance Imaging, 2016 Gadolinium is highly toxic. Gadolinium-based contrast agents (GBCAs) consist of gadolinium ions and a chelating agent that binds the gadolinium ion tightly in order not to manifest its toxicity. Knowledge regarding gadolinium deposition in patients with normal renal function has advanced dramatically.
Yudai Nakai, Keiko Toyoda, Hiroshi Oba
exaly +3 more sources
Comparative Pharmacokinetics of Gadolinium DTPA and Gadolinium Chloride
Investigative Radiology, 1988An intravenous injection of 153Gd-labeled gadolinium-DTPA or gadolinium chloride was given to 60 rats, which were killed either 15, 40, 120, 300, 900, or 3600 seconds later. Tissue concentrations of gadolinium in the blood, liver, spleen, stomach, pancreas, renal cortex, renal medulla, lungs, heart, adrenals, gluteal muscle, fat, skin, thymus, brain ...
P B, Dean +3 more
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Renal Tolerance of Gadolinium-DOTA and Gadolinium-DTPA in Rats
Investigative Radiology, 1994Although gadolinium chelates are mainly eliminated by the kidney, there is limited information about their effects. The renal tolerance of these compounds on renal function in an in vivo rat model are evaluated.A combination of renal ischemia and intrarenal iodinated contrast agent infusion (diatrizoate) led to a reproducible and reversible model of ...
G, Brillet +4 more
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Where does the gadolinium go? A review into the excretion and retention of intravenous gadolinium
Journal of Medical Imaging and Radiation Oncology, 2023SummaryGadolinium‐based contrast agents (GBCAs) are commonly used in medical imaging. Most intravenously (IV) administered gadolinium is excreted via the kidneys, and pathological retention in renal failure leading to nephrogenic systemic fibrosis (NSF) is well described.
Pranav Sharma +2 more
openaire +4 more sources
New Dual Mode Gadolinium Nanoparticle Contrast Agent for Magnetic Resonance Imaging [PDF]
PLoS ONE, 2009 Liposomal-based gadolinium (Gd) nanoparticles have elicited significant interest for use as blood pool and molecular magnetic resonance imaging (MRI) contrast agents. Previous generations of liposomal MR agents contained gadolinium-chelates either within
Ananth V Annapragada +2 more
exaly +2 more sources