Results 261 to 270 of about 339,221 (330)

Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging. [PDF]

open access: yesNat Commun
Zhu Y   +11 more
europepmc   +1 more source

Data‐driven analysis of the spatial dependence of grouting efficiency during tunnel excavation

open access: yesDeep Underground Science and Engineering, EarlyView.
Prediction of grouting efficiency using machine learning is enhanced by adopting a training strategy that accounts for the grouting process across multiple rounds. Abstract Grouting with water–cement mixtures is the most widely used and cost‐effective method for managing excess water inflow during tunnel construction.
Huaxin Liu, Xunchang Fei, Wei Wu
wiley   +1 more source

Profiling HIV1-host protein-protein interaction networks in patient-derived exosome proteins: impact on pathophysiology and innate immune pathways. [PDF]

open access: yesVirol J
Fatima N   +14 more
europepmc   +1 more source

Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Bones develop to structurally balance strength and mobility. Bone developmental dynamics are influenced by whether an animal is ambulatory at birth. Precocial species, which are ambulatory at birth, develop advanced skeletal maturity in utero and experience postnatal development under mechanical loading.
Christopher J. Panebianco   +8 more
wiley   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki   +6 more
wiley   +1 more source

Quantitative HILIC-Q-TOF-MS Analysis of Glycosaminoglycans and Non-reducing End Carbohydrate Biomarkers via Glycan Reductive Isotopic Labeling. [PDF]

open access: yesAnal Chem
Basu A   +12 more
europepmc   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff   +6 more
wiley   +1 more source

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