Results 131 to 140 of about 2,355,604 (311)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

A High-Gain Cell Enhancer

open access: yes, 1992
A cell enhancer that offers a combination of high-grain and high output power with extremely good linearity is described. The prototype repeater offers an active gain of at least 100 dB over a bandwidth of several megahertz. A linearized broadband amplifier is combined with a novel system for reducing the effect of the damaging mutual coupling between ...
Slingsby, WT, McGeehan, JP
openaire   +2 more sources

Speech enhancement using hybrid gain factor in critical-Band-Wavelet Packet Transform

open access: yes, 2012
[[abstract]]Noise masking threshold (NMT) has been extensively applied in wavelet-based speech enhancement. A gain factor is typically derived according to the NMT to suppress the additive noise.
陸清達;Lu, Ching-Ta
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Gain and Bandwidth Enhancement of 3D-Printed Short Backfire Antennas Using Rim Flaring and Iris Matching

open access: yesSensors
In this article, we present new design techniques to improve the gain and impedance bandwidth of short backfire antennas. For the gain enhancement procedure, our approach was to flare the rim of the antenna, which simultaneously led to an increase in the
Yewande Mariam Aragbaiye   +1 more
doaj   +1 more source

Bandwidth and gain enhancement of composite right left handed metamaterial transmission line planar antenna employing a non foster impedance matching circuit board. [PDF]

open access: yesSci Rep, 2021
Alibakhshikenari M   +10 more
europepmc   +1 more source

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