Results 181 to 190 of about 185,187 (300)

Late-onset ornithine transcarbamylase deficiency mimicking cognitive, behavioral and gait disorders: a case report and literature review. [PDF]

Postep Psychiatr Neurol
Przybycień A, Hołub-Kucharska W, Węgielnik J, Sławek J.   +3 more
europepmc   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

The comparison of gait disorders among different motor subtypes in Parkinson's disease patients during the early and middle stages. [PDF]

Clin Park Relat Disord
Mei J, Wang Y, Zhu D, Li Y, Gu K, Wei Z, Han X, Li Q, Jiang S, Zhang Y.   +9 more
europepmc   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Higher-level gait disorders: a population-based study on prevalence, quality of life, depression and confidence in gait and balance. [PDF]

BMJ Neurol Open
Larsson J, Hansson W, Israelsson Larsen H, Koskinen LD, Eklund A, Malm J.   +5 more
europepmc   +1 more source

Fall prediction in neurological gait disorders: differential contributions from clinical assessment, gait analysis, and daily-life mobility monitoring. [PDF]

J Neurol, 2021
Schniepp R, Huppert A, Decker J, Schenkel F, Schlick C, Rasoul A, Dieterich M, Brandt T, Jahn K, Wuehr M.   +9 more
europepmc   +1 more source

A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury

Advanced Science, EarlyView.
A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang, Hao Hu, Yijun Li, Lintao Hu, Chenhui Gu, Yiwei Zhu, Jing Huang, Na Li, Shuqi Jiang, Shouyan Zu, Jiachen Xu, Yining Wang, Ke Yang, Pengfei Chen, Liqing Shangguan, Yongcheng Wang, Shunwu Fan, Xianfeng Lin, Qingqing Wang   +18 more
wiley   +1 more source

Mechanical peripheral stimulation for the treatment of gait disorders in patients with Parkinson's disease: a multi-centre, double-blind, crossover randomized controlled trial. [PDF]

J Neuroeng Rehabil
De Pandis MF, Tomino C, Proietti S, Rotondo R, Gaglione M, Casali M, Corbo M, di Biase L, Galli M, Goffredo M, Stocchi F.   +10 more
europepmc   +1 more source

Functional gait disorders: A sign-based approach. [PDF]

Neurology, 2020
Nonnekes J, Růžička E, Serranová T, Reich SG, Bloem BR, Hallett M.   +5 more
europepmc   +1 more source

Low to moderate relationships between gait and postural responses in Parkinson disease [PDF]

, 2017
Duncan, Ryan P, Earhart, Gammon M, McNeely, Marie E, Seidler, Katie J, Sutter, Ellen N   +4 more
core   +1 more source