Results 61 to 70 of about 100,148 (251)

Gait disorders are associated with non-cardiovascular falls in elderly people: a preliminary study

BMC Geriatrics, 2005
Background The association between unexplained falls and cardiovascular causes is increasingly recognized. Neurally mediated cardiovascular disorders and hypotensive syndromes are found in almost 20 percent of the patients with unexplained falls ...
Schapira Marcelo, Montero-Odasso Manuel, Duque Gustavo, Soriano Enrique R, Kaplan Roberto, Camera Luis A   +5 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

GaitMed: A Medical Gait Dataset and Benchmark for Musculoskeletal Disease Classification

Human-Centric Intelligent Systems
Gait analysis has become a powerful tool for understanding, diagnosing, and monitoring musculoskeletal disorders. However, existing gait datasets primarily focus on human identification tasks, with limited applications in the medical diagnostic domain ...
Weiya Shi, Changjiang Wu, Xinyu Dong, Saiyang Liu, Yue Guo   +4 more
doaj   +1 more source

Clinical analysis of balance and gait disorders after subthalamic nucleus deep brain stimulation in patients with Meige's syndrome

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To summarize and analyze the data of postural balance and gait disorders in patients with Meige's syndrome (MS) who underwent subthalamic nucleus deep brain stimulation (STN ⁃ DBS).
Ning WANG, Xiao⁃song WANG, Yu⁃peng GUO, Zong⁃hui FU, Guo⁃qiang CHEN, Lin WANG   +5 more
doaj  

Eyewear Equipped with a Triaxial Accelerometer Detects Age-Related Changes in Ambulatory Activity

DigitCult@Scientific Journal on Digital Cultures, 2017
Aging is known as a risk factor for gait disorders, which lead to reduced quality of life. Gait disorders can potentially be a sign of a preclinical phase of neurological diseases.
Shigeyuki Ikeda, Susumu Ichinohe, Ryuta Kawashima   +2 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Wearable Sensor-Based Daily Life Walking Assessment of Gait for Distinguishing Individuals With Amnestic Mild Cognitive Impairment

Frontiers in Aging Neuroscience, 2019
Objectives: To characterize gait disorders in patients with amnestic mild cognitive impairment (aMCIs) and determine the association between the performance of the gait function and cognition.Methodology: In this study, we enrolled 38 patients with aMCI ...
Haiqun Xie, Yukai Wang, Shuai Tao, Shuyun Huang, Chengguo Zhang, Zeping Lv   +5 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi, Damiano Marastoni, Agnese Tamanti, Pietro Biasi, Valentina Visani, Annalisa Colombi, Tom A. Fuchs, Monica Sicchieri, Chiara Eccher, Francesco Guarnaccia, Milena Calderone, Valentina Camera, Francesca Benedetta Pizzini, Roberta Magliozzi, Marco Castellaro, Massimiliano Calabrese   +15 more
wiley   +1 more source

Effects of rivastigmine on gait in patients with neurodegenerative disorders: A systematic review and meta-analysis.

PLoS ONE
Background & aimsGait disturbances are commonly observed in patients with neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and higher-level gait disorders, which are associated with cholinergic deficits.
Sung Ryul Shim, Jong-Yeup Kim, Kyum-Yil Kwon, Jieun Shin, Yungjin Lee, Seon-Min Lee   +5 more
doaj   +1 more source