Results 111 to 120 of about 149 (148)

Silicosarcoidosis: Histologic and Clinical Features of an Occupational Granulomatous Disease

American Journal of Industrial Medicine, Volume 68, Issue 6, Page 491-507, June 2025.
ABSTRACT Sarcoidosis is a multisystem inflammatory disease of unknown etiology. Growing evidence indicates that occupational exposure to respirable crystalline silica (RCS) is associated with an increased incidence of sarcoidosis. Yet a diagnosis of sarcoidosis rarely prompts investigation to identify preventable exposures.
Jeremy T. Hua, Carlyne D. Cool, Einat Fireman Klein, Yochai Adir, Lukas J. Lee, Lauren M. Zell‐Baran, Robert A. Cohen, Richard C. Kraus, E. Brigitte Gottschall, Silpa D. Krefft, Charles Van Hook, Cecile S. Rose   +11 more
wiley   +1 more source

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

iMeta, Volume 4, Issue 3, June 2025.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang, Rong Li, Yasong Liu, Jinliang Liang, Yihang Gong, Cuicui Xiao, Jianye Cai, Tingting Wang, Qiang You, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Yingcai Zhang, Yang Yang, Hua Li, Jia Yao, Qi Zhang, Jun Zheng   +17 more
wiley   +1 more source

The microbiologist's guide to metaproteomics

iMeta, Volume 4, Issue 3, June 2025.
Metaproteomics within the multi‐omics framework provides a comprehensive view of microbial systems by identifying proteins, quantifying their levels, detecting posttranslational modifications (PTMs), mapping protein–protein interactions (PPIs), and localizing proteins.
Tim Van Den Bossche, Jean Armengaud, Dirk Benndorf, Jose Alfredo Blakeley‐Ruiz, Madita Brauer, Kai Cheng, Marybeth Creskey, Daniel Figeys, Lucia Grenga, Timothy J. Griffin, Céline Henry, Robert L. Hettich, Tanja Holstein, Pratik D. Jagtap, Nico Jehmlich, Jonghyun Kim, Manuel Kleiner, Benoit J. Kunath, Xuxa Malliet, Lennart Martens, Subina Mehta, Bart Mesuere, Zhibin Ning, Alessandro Tanca, Sergio Uzzau, Pieter Verschaffelt, Jing Wang, Paul Wilmes, Xu Zhang, Xin Zhang, Leyuan Li, The Metaproteomics Initiative   +31 more
wiley   +1 more source

The effect of an electronic health record choice architecture intervention on efficient diuretic use: A research report

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 8, Issue 6, Page 439-444, June 2025.
Abstract Introduction Oral metolazone and intravenous (IV) chlorothiazide have comparable diuretic efficacy and safety, although IV chlorothiazide is significantly more expensive. The use of electronic health record (EHR)‐based choice architecture interventions on the efficient use of diuretics remains unexplored.
Joshua A. Jacobs, Nicholas S. Hendren, Kristin S. Alvarez, Leah J. Stinson, Chris Mathew, Michael Harms, Griffin Bullock, Tamara Cisowska, Kimberly J. Terry, Irene Z. Pan, Jake Goldstein, James C. Fang, Sandeep R. Das, Spencer J. Carter   +13 more
wiley   +1 more source

Accuracy and interpretability of smartwatch electrocardiogram for early detection of atrial fibrillation: A systematic review and meta‐analysis

Journal of Arrhythmia, Volume 41, Issue 3, June 2025.
The smartwatch ECG algorithm achieved 86% sensitivity and 94% specificity with an sAUC of 96%, while manual readings by trained personnel reached 96% sensitivity, 95% specificity, and an sAUC of 98% in a brand‐specific subgroup analysis. These findings demonstrate that the smartwatch ECG detects AFib, although 3% of results are unreadable.
Muhammad Iqhrammullah, Asnawi Abdullah, Hermansyah, Fahmi Ichwansyah, Hafnidar A. Rani, Meulu Alina, Artha M. T. Simanjuntak, Derren D. C. H. Rampengan, Seba Talat Al‐Gunaid, Naufal Gusti, Arditya Damarkusuma, Edza Aria Wikurendra   +11 more
wiley   +1 more source

In Vitro Validation of Pulsed Electromagnetic Field (PEMF) as an Effective Countermeasure Against Inflammatory‐Mediated Intervertebral Disc Degeneration

JOR SPINE, Volume 8, Issue 2, June 2025.
ABSTRACT Background Intervertebral disc (IVD) degeneration (IDD) is the main contributor to chronic low back pain (LBP), the leading cause of disability worldwide, with a significant impact on the quality of life and health of common people. The etiology of IDD is still unclear, but it has been largely demonstrated the crucial role of inflammation and ...
Laura Guarnaccia, Laura Begani, Silvana Pileggi, Mauro Pluderi, Stefano Borsa, Claudia Fanizzi, Massimiliano Domenico Rizzaro, Giorgio Fiore, Laura Fontana, Rolando Campanella, Chiara Cordiglieri, Chiara Gaudino, Giovanni A. Alotta, Monica Miozzo, Emanuele Garzia, Emanuela Barilla, Lorenzo Fassina, Laura Riboni, Marco Locatelli, Giovanni Marfia, Stefania E. Navone   +20 more
wiley   +1 more source

Efficacy of Topical Nigella sativa Oil for Oral Wound Healing in Rats

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 3, June 2025.
ABSTRACT Objective This study aimed to examine the effect of topical Nigella sativa oil (NSO) on intraoral wound healing in rats. Materials and Methods Forty‐eight female Wistar albino rats (2.5–3 months old) were assigned to two groups (n = 24 each): A control group receiving no treatment and an NSO group receiving a topical application of 1 cc NSO. A
Alper Tabaru, Sedat Rüzgar
wiley   +1 more source

Plant‐Based Mycetoma Inhibitors Targeting the 50S Ribosomal Protein of Nocardia brasiliensis: In Silico Approach

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
In‐silico drug discovery pipeline for Mycetoma caused by Nocardia brasiliensis. A library of 1034 phytocompounds was screened to identify potent inhibitors, with Parviflorone F showing strong binding and stability against the 50S ribosomal unit. Molecular dynamics confirmed its inhibitory potential, offering a promising therapeutic candidate.
Sandra Jose, Manjunathan Jagadeesan, Meenambiga Setti Sudharsan, Pasiyappazham Ramasamy, Shyamala Gowri, Muthu Thiruvengadam, Sowmya Hari, Baskar Venkidasamy   +7 more
wiley   +1 more source

Use of 3He Neutron Sensors for Planetary Penetrator Experiments

Earth and Space Science, Volume 12, Issue 6, June 2025.
Abstract This paper provides a report on a test that was carried out over 20 years ago to demonstrate that two 3He gas proportional neutron sensors could survive a high‐impact penetrator test. This test was carried out as part of a risk reduction effort for a proposed mission that would send multiple penetrators to landing locations within lunar ...
David J. Lawrence, Bruce L. Barraclough, Richard C. Elphic, Paul G. Lucey   +3 more
wiley   +1 more source

The Radio Wave Polarization of Saturn Lightning Observed by Cassini

Journal of Geophysical Research: Space Physics, Volume 130, Issue 6, June 2025.
Abstract We investigate the polarization of the radio waves emitted by lightning in Saturn's atmosphere, which are referred to as SEDs for Saturn Electrostatic Discharges. Using the complete SED data set retrieved by Cassini's RPWS (Radio and Plasma Wave Science) instrument we found that the circular polarization of SEDs below a frequency of 2 MHz ...
G. Fischer, M. Imai, U. Taubenschuss, D. Píša, W. S. Kurth   +4 more
wiley   +1 more source