Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Hepatology, EarlyView., 2022 Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres +21 more
wiley +1 more source
Early Starbursts and Magnetic Field Generation in Galaxy Clusters
The Astrophysical Journal, 2000 24 pages, 4 figures, to appear in ...
Heinrich J. Völk +2 more
openaire +3 more sources
New insights into the star formation histories of candidate intermediate-age early-type galaxies from K-band imaging of globular clusters [PDF]
, 2011 We investigate the age and metallicity distributions of bright globular clusters (GCs) in the candidate intermediate-age early-type galaxies NGC 3610, 584 and 3377 using a combination of new Gemini's Near InfraRed Imager and Spectrometer K -band ...
I. Georgiev +9 more
semanticscholar +1 more source
On a Generalized Mass-Velocity Relation for Disk Galaxies and Galaxy Clusters
, 2021 We consolidate the BFJ and BTF (MVD) relations into a generalized Scaling Mass Velocity Relation applicable to both pressure-supported galaxy clusters and rotation-supported galaxies. Unlike MOND inspired relations containing a characteristic acceleration scale and its normalization factor, our proposal is dependent on observed dynamic surface mass ...
openaire +2 more sources
Ultra-diffuse Galaxies Are a Subset of Cluster Dwarf Elliptical/Spheroidal Galaxies [PDF]
, 2018 Since 2015 there has been a great deal of interest in a supposed new class of galaxy called Ultra Diffuse Galaxies (UDGs). These are large systems with sizes $> 1.5$ kpc and have surface brightness values which are $\mu > 25$ mag arcsec$^{-2}$.
C. Conselice
semanticscholar +1 more source
The Next Generation Virgo Cluster Survey (NGVS). XXX. Ultra-diffuse Galaxies and Their Globular Cluster Systems [PDF]
The Astrophysical Journal, 2020 Abstract We present a study of ultra-diffuse galaxies (UDGs) in the Virgo Cluster based on deep imaging from the Next Generation Virgo Cluster Survey. Applying a new definition for the UDG class based on galaxy scaling relations, we define samples of 44 and 26 UDGs using expansive and restrictive selection criteria, respectively. Our UDG
Chengze Liu +17 more
openaire +8 more sources
The Next Generation Virgo Cluster Survey. XXXIV. Ultracompact Dwarf Galaxies in the Virgo Cluster
The Astrophysical Journal Supplement Series, 2020 Abstract We present a study of ultracompact dwarf (UCD) galaxies in the Virgo cluster based mainly on imaging from the Next Generation Virgo Cluster Survey (NGVS). Using ∼100 deg2 of u*giz imaging, we have identified more than 600 candidate UCDs, from the core of Virgo out to its virial radius.
Liu, Chengze +30 more
openaire +9 more sources
STAR CLUSTERS, GALAXIES, AND THE FUNDAMENTAL MANIFOLD [PDF]
, 2010 We explore whether global observed properties, specifically half-light radii, mean surface brightness, and integrated stellar kinematics, suffice to unambiguously differentiate galaxies from star clusters, which presumably formed differently and lack ...
D. Zaritsky +2 more
semanticscholar +1 more source
Generation and Implications of Post-Merger Turbulence in Clusters of Galaxies [PDF]
Symposium - International Astronomical Union, 1998 Observations in X-ray and optical suggest that mergers of sub-clusters with galaxy clusters are quite common (for Coma see e.g., White et al. 1993; Colless & Dunn 1996; Ishizaka & Mineshige 1996). A merger leads to violent relaxation of the dissipationless dark matter resulting in a time-dependent gravitational potential. This in turn generates
openaire +2 more sources
A Census of Ultra-Compact Dwarf Galaxies in Nearby Galaxy Clusters [PDF]
, 2010 Ultra-compact dwarf galaxies (UCDs) are predominatly found in the cores of nearby galaxy clusters. Besides the Fornax and Virgo cluster, UCDs have also been confirmed in the twice as distant Hydra I and Centaurus clusters.
M. Hilker
semanticscholar +1 more source