Results 31 to 40 of about 2,679,859 (247)

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

The Origin of the Mass-Metallicity Relation: Insights from 53,000 Star-forming Galaxies in the Sloan Digital Sky Survey [PDF]

, 2004
We utilize Sloan Digital Sky Survey imaging and spectroscopy of ~53,000 star-forming galaxies at z ~ 0.1 to study the relation between stellar mass and gas-phase metallicity.
C. Tremonti, T. Heckman, G. Kauffmann, J. Brinchmann, S. Charlot, S. White, M. Seibert, E. Peng, D. Schlegel, A. Uomoto, M. Fukugita, J. Brinkmann   +11 more
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Mimicking Symmetry‐Breaking Einstein Ring by Optical Lens

Advanced Photonics Research, EarlyView.
This article uses an optical lens to emulate the gravitational lensing effect and observe the Einstein ring (ER) patterns. The symmetry‐breaking ER, i.e., Einstein cross, is observed utilizing a rotation‐symmetry‐breaking hemi‐ellipsoid lens. Deformed Einstein cross patterns induced by noncollinearly alignment of the light source–lens–observer are ...
Jun‐Liang Duan, Wen Xiao, Minyong Guo, Tong Liu, Huanyang Chen, Jin‐Hui Chen   +5 more
wiley   +1 more source

A Cosmological Framework for the Co-Evolution of Quasars, Supermassive Black Holes, and Elliptical Galaxies. I. Galaxy Mergers and Quasar Activity [PDF]

, 2007
We develop a model for the cosmological role of mergers in the evolution of starbursts, quasars, and spheroidal galaxies. By combining theoretically well-constrained halo and subhalo mass functions as a function of redshift and environment with empirical
P. Hopkins, L. Hernquist, T. J. Cox, D. Keres̆   +3 more
semanticscholar   +1 more source

Scintillation Response of 0D Cs3Cu2I5 Thin Layers to Light‐ and Heavy‐Ion Irradiation

Advanced Photonics Research, EarlyView.
Driven by increasing interest in uncovering the remarkable photoluminescence quantum yield of Cs3Cu2I5, polycrystalline thin layers are synthesized to investigate its radioluminescence response to energetic ions. Its spectroscopic capability is assessed in a wide range of ion mass and internal excitation processes are explored.
Mátyás Hunyadi, Attila Csík, Cintia Hajdu, Csaba Janáky, István Rajta, Gergely F. Samu, Lóránt Csige   +6 more
wiley   +1 more source

THE COSMOS2015 CATALOG: EXPLORING THE 1 < z < 6 UNIVERSE WITH HALF A MILLION GALAXIES [PDF]

, 2016
We present the COSMOS2015 catalog, which contains precise photometric redshifts and stellar masses for more than half a million objects over the 2deg2 COSMOS field.
C. Laigle, H. McCracken, O. Ilbert, B. Hsieh, I. Davidzon, P. Capak, G. Hasinger, J. Silverman, C. Pichon, J. Coupon, H. Aussel, D. L. Borgne, K. Caputi, P. Cassata, Yu-Yen Chang, F. Civano, F. Civano, J. Dunlop, J. Fynbo, J. Kartaltepe, A. Koekemoer, O. Fèvre, E. Floc’h, A. Leauthaud, S. Lilly, Lihwai Lin, S. Marchesi, S. Marchesi, B. Milvang-Jensen, M. Salvato, D. Sanders, N. Scoville, V. Smolčić, M. Stockmann, Y. Taniguchi, L. Tasca, S. Toft, Mattia Vaccari, J. Zabl   +38 more
semanticscholar   +1 more source

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

Advanced Science, EarlyView.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu, Amarnath Marudamuthu, Khadija Kakar, Hamida Hamida, Shruthi Thada, Rohan Gupta, Kiesha Wilson, Taylor Carter, Yin Zhong, Archana Saxena, Xiaoming Yang, Narendra Singh, Philip Brandon Busbee, Jie Li, Monica Garcia‐Buitrago, Prakash Nagarkatti, Mitzi Nagarkatti   +16 more
wiley   +1 more source

The Herschel* PEP/HerMES luminosity function - I. Probing the evolution of PACS selected Galaxies to z ≃ 4 [PDF]

, 2013
We exploit the deep and extended far-IR data sets (at 70, 100 and 160 mu m) of the Herschel Guaranteed Time Observation (GTO) PACS Evolutionary Probe (PEP) Survey, in combination with the Herschel Multi-tiered Extragalactic Survey data at 250, 350 and ...
C. Gruppioni, F. Pozzi, G. Rodighiero, I. Delvecchio, S. Berta, L. Pozzetti, G. Zamorani, P. Andreani, A. Cimatti, O. Ilbert, E. L. Floch, D. Lutz, B. Magnelli, L. Marchetti, L. Marchetti, P. Monaco, R. Nordon, S. Oliver, P. Popesso, L. Riguccini, I. Roseboom, I. Roseboom, D. Rosario, M. Sargent, Mattia Vaccari, Mattia Vaccari, B. Altieri, H. Aussel, Á. Bongiovanni, J. Cepa, E. Daddi, H. Domínguez-Sánchez, H. Domínguez-Sánchez, D. Elbaz, N. F. Schreiber, R. Genzel, A. Iribarrem, M. Magliocchetti, R. Maiolino, A. Poglitsch, A. P. Garćıa, M. Sánchez-Portal, E. Sturm, L. Tacconi, I. Valtchanov, A. Amblard, V. Arumugam, M. Béthermin, J. Bock, J. Bock, A. Boselli, V. Buat, D. Burgarella, N. Castro-RodrÍguez, N. Castro-RodrÍguez, A. Cava, P. Chanial, D. Clements, A. Conley, A. Cooray, A. Cooray, C. Dowell, C. Dowell, E. Dwek, S. Eales, A. Franceschini, J. Glenn, M. Griffin, E. Hatziminaoglou, E. Ibar, K. Isaak, R. Ivison, R. Ivison, G. Lagache, L. Levenson, L. Levenson, N. Lu, S. Madden, B. Maffei, G. Mainetti, Hieu Nguyen, Hieu Nguyen, B. O’Halloran, M. Page, P. Panuzzo, A. Papageorgiou, C. Pearson, C. Pearson, I. Pérez-Fournon, I. Pérez-Fournon, M. Pohlen, D. Rigopoulou, D. Rigopoulou, M. Rowan‐Robinson, B. Schulz, D. Scott, N. Seymour, N. Seymour, D. Shupe, A. Smith, J. Stevens, M. Symeonidis, M. Trichas, K. Tugwell, L. Vigroux, Lian-tao Wang, G. Wright, C. Xu, M. Zemcov, M. Zemcov, S. Bardelli, M. Carollo, T. Contini, O. Fèvre, S. Lilly, V. Mainieri, A. Renzini, M. Scodeggio, E. Zucca   +118 more
semanticscholar   +1 more source

Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa

Advanced Science, EarlyView.
Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang, Xiaofei Wang, Chengli Liu, Kaixuan He, Xiu‐Li Hou, Haofei Luo, Shuaibin Zhang, Changqing You, Yajun Jia, Fuqiang Wang, Xianwei Song, Guodao Liu, Xian Deng, Xiaofeng Cao   +13 more
wiley   +1 more source