Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres+21 more
wiley +1 more source
Linking dust emission to fundamental properties in galaxies: the low-metallicity picture [PDF]
Aims. In this work, we aim to provide a consistent analysis of the dust properties from metal-poor to metal-rich environments by linking them to fundamental galactic parameters. Methods.
A. Rémy-Ruyer+19 more
semanticscholar +1 more source
Surface density: a new parameter in the fundamental metallicity relation of star-forming galaxies [PDF]
Star-forming galaxies display a close relation among stellar mass, metallicity and star-formation rate (or molecular-gas mass). This is known as the fundamental metallicity relation (FMR) (or molecular-gas FMR), and it has a profound implication on ...
T. Hashimoto, T. Goto, R. Momose
semanticscholar +1 more source
The SAMI Galaxy Survey: stellar population and structural trends across the Fundamental Plane [PDF]
We study the Fundamental Plane (FP) for a volume- and luminosity-limited sample of 560 early-type galaxies from the SAMI survey. Using r-band sizes and luminosities from new multi-Gaussian expansion photometric measurements, and treating luminosity as ...
F. d’Eugenio+18 more
semanticscholar +1 more source
ONE PLANE FOR ALL: MASSIVE STAR-FORMING AND QUIESCENT GALAXIES LIE ON THE SAME MASS FUNDAMENTAL PLANE AT z ∼ 0 AND z ∼ 0.7 [PDF]
Scaling relations between galaxy structures and dynamics have been studied extensively for early- and late-type galaxies, both in the local universe and at high redshifts.
R. Bezanson, M. Franx, P. V. van Dokkum
semanticscholar +1 more source
Improved strong lensing modelling of galaxy clusters using the Fundamental Plane: Detailed mapping of the baryonic and dark matter mass distribution of Abell S1063 [PDF]
Aims. From accurate photometric and spectroscopic information, we build the Fundamental Plane (FP) relation for the early-type galaxies of the cluster Abell S1063.
G. Granata+8 more
semanticscholar +1 more source
Analysis of the escape in systems with four exit channels
In this paper, we have performed a numerical investigation of the escape of a particle from two different dynamical systems with the same number of exit channels. We have chosen specific values of the parameters of the systems so that the openings of the potential well in both systems are approximately of the same size.
Juan F. Navarro+2 more
wiley +1 more source
Discovery of the local counterpart of disc galaxies at z > 4: The oldest thin disc of the Milky Way using Gaia-RVS [PDF]
JWST recently detected numerous disc galaxies at high redshifts, and there have been observations of cold disc galaxies at z > 4 with ALMA. In the Milky Way (MW), recent studies highlight the presence of metal-poor stars in cold-disc orbits, suggesting ...
S. Nepal+7 more
semanticscholar +1 more source
Modelling the ages and metallicities of early-type galaxies in Fundamental Plane space [PDF]
Recent observations have probed the formation histories of nearby elliptical galaxies by tracking correlations between the stellar population parameters, age and metallicity, and the structural parameters that enter the Fundamental Plane, size Re and ...
L. Porter+6 more
semanticscholar +1 more source
MASSIV: Mass Assembly Survey with SINFONI in VVDS - VI. Metallicity-related fundamental relations in star-forming galaxies at 1 < z < 2 [PDF]
Aims. The MASSIV (Mass Assembly Survey with SINFONI in VVDS) project aims at finding constraints on the different processes involved in galaxy evolution.
C. Divoy+19 more
semanticscholar +1 more source