Results 11 to 20 of about 1,075 (180)
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Hepatology, EarlyView., 2022 Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres +21 more
wiley +1 more source
Scale Interactions and Galaxy Evolution [PDF]
Astrophysics and Space Science, 2003 To understand galaxies and their evolution, it is necessary to describe how the different scales interact: how the microscopic physics, such as star formation, or the large scale physics, such as galaxy interactions may modify the galaxy global shapes.
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Advanced Materials, EarlyView.A fully flexible ion‐gel‐gated graphene‐channel transistor driven by a triboelectric nanogenerator enables self‐powered tactile sensing and synaptic learning. Mimicking spike‐rate‐dependent plasticity, the device exhibits frequency‐selective potentiation and depression, supporting rate‐coded neuromorphic computation even under flex.
Hanseong Cho +3 more
wiley +1 more source
Bar-spheroid interaction in galaxies
The Astrophysical Journal, 1992 The secular evolution of barred galaxies is explored using N-body simulation and linear analysis. In particular, we examine the interaction between bars and spheroidal components of galaxies. According to our calculations, this interaction drives secular transfer of angular momentum from bars to spheroids, primarily through resonant coupling.
Hernquist, Lars, Weinberg, Martin D.
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Advanced Materials Technologies, EarlyView.This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane +4 more
wiley +1 more source
Chemodynamical evolution of interacting galaxies
Astrophysics and Space Science, 2002 4 pages, 3 figures, to be published in "The Evolution of Galaxies. II. Basic Building Blocks", ed. M.
Combes, F., Melchior, A. L.
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Advanced Materials Technologies, EarlyView.Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale +3 more
wiley +1 more source
Radio Diagnostics Of Galaxy Interactions [PDF]
Symposium - International Astronomical Union, 1999 The Hickson Compact Groups (Hickson 1982) are relatively isolated systems of galaxies with projected separations comparable to the diameters of the galaxies themselves and are an ideal laboratory for the study of the effects of interactions on the various properties of galaxies.
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Advanced Robotics Research, EarlyView.This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino +7 more
wiley +1 more source
A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Advanced Science, EarlyView.Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source