Results 31 to 40 of about 1,750 (198)

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Form flows function: Learner‐centered game Re‐design in a STEM classroom

British Educational Research Journal, EarlyView.
Abstract Re‐designing games facilitates interest‐driven learning and immerses learners in systems thinking. However, there are limited studies exploring how the form and function of tabletop games influence learners' design decisions and learning experiences. To address this gap, we conducted a mixed‐methods study in a STEM classroom in western Canada.
Farzan Baradaran Rahimi, Beaumie Kim, Shima Dadkhahfard   +2 more
wiley   +1 more source

Investigation on tunnel stability considering pipe‐roof support with transparent soil technology

Deep Underground Science and Engineering, EarlyView.
This study integrates transparent soil technology, 3D reconstruction and numerical simulation to captures the full‐field deformation of shield tunnel instability. Results demonstrate that pipe‐roof support enhances stability via the “soil‐arching barrier effect,” effectively restraining failure wedge development by extending stress transfer paths ...
Zhi Jia, Yunpeng Ji, Zhao Lu, Honghua Zhao, Limin Zhang   +4 more
wiley   +1 more source

Ragomics‐Meta: An open‐source, scalable, reproducible, and extensible multi‐omics analysis workflow

iMetaOmics, EarlyView.
Ragomics‐Meta is an open‐source, scalable, and reproducible multi‐omics workflow for metabolism‐centered analysis (https://www.raganetwork.com/). It integrates scRNA/snRNA‐seq, spatial transcriptomics, scATAC‐seq, and metabolomics modules to support quality control, dimensionality reduction, clustering, differential expression and accessibility ...
Zeping Gui, Huidong Su, Yuhao Chen, Jixing Yuan, Yexiu Gao, Ze Yu, Jing Zhang, Qingyi Zhu, Min Gu, Mulong Du, Zijie Wang, Ming Chen   +11 more
wiley   +1 more source

The effect of the galaxy environment on the size and structure of galaxies [PDF]

, 2013
In this thesis, we explore the effect of the galaxy environment on the physical size and structure of the stellar distribution for relatively local galaxies (z < 0.3) using Hubble Space Telescope/Advanced Camera for Surveys imaging and data from the Space Telescope A901/2 galaxy evolution survey (STAGES).
openaire   +2 more sources

THE SHAPE OF GALAXY STRUCTURES

The Astrophysical Journal, 2009
An analysis is presented for a statistically complete sample of 547 galaxy structures with z ≤ 0.16, each containing at least 10 objects. The sample was divided according to structure richness, representing 10 richness classes, with the distribution of ellipticities differing among individual classes.
Elena Panko, Teresa Juszczyk, Monika Biernacka, Piotr Flin   +3 more
openaire   +1 more source

Wekemo Bioincloud 2026: An AI‐enabled platform for standardized multi‐omics data analyses

iMeta, EarlyView.
An AI‐powered multi‐omics cloud platform integrating 41 standardized workflows, 126 visualization tools, and full‐lifecycle research intelligence to enable accessible, reproducible, and end‐to‐end integrative multi‐omics analysis. Abstract The rapid expansion of multi‐omics data has created an increasing demand for accessible and reproducible platforms
Yunyun Gao, Guoxing Zhang, Chengrui Wang, Hao Xu, Zhanhui Yu, Shunyao Jiang, Yong‐Xin Liu   +6 more
wiley   +1 more source

Cis–Trans Rotational Isomerism of Formic Acid, Sulfur, and Selenium Analogues and Their Dimers: Chemical Kinetics Under Interstellar Conditions

International Journal of Chemical Kinetics, EarlyView.
ABSTRACT We present chemical kinetic rate constants for the cis to trans isomerisation or rotamerization of monomeric seleno‐, thio‐, and formic acids and that of three of their dimeric species, based on variational transition state theory and multidimensional tunneling calculations in the gas‐phase, from 10 K to 300 K. These provide, firstly, reliable
Judith Wurmel, John M. Simmie
wiley   +1 more source

Patterns of wild meat and other protein consumption in the periphery of Salonga National Park, Democratic Republic of the Congo

People and Nature, EarlyView.
Abstract In Central Africa, human activities are severely impacting terrestrial and aquatic wildlife, threatening the food security of millions of people. Accordingly, sustainable use of wildlife is crucial for the nutrition and livelihoods of many rural communities in the region.
Zolo Admettons, Mattia Bessone, Josué Ausse Baraka, Josué Engombe Botomia, Espérance Miezi, Bénédicte Nsilu, Jonathan Nkamisha Mukole, Michel Opelele Omeno, Jean Semeki Ngabinzeke, Barbara Fruth   +9 more
wiley   +1 more source

Human Sustainability Leadership and Employee Wellbeing (Flourishing) in Organizations

Sustainable Development, EarlyView.
ABSTRACT This qualitative case study research examines how designing for human sustainability leadership (HSL) affects employee wellbeing (flourishing) (HWBF) in organizations. It is undertaken at a university in the United Kingdom including academics and administrators.
Elli Meleti
wiley   +1 more source