Results 201 to 210 of about 675,630 (383)

Tumor desialylation surpasses anti‐PD‐L1 checkpoint therapy in restoring anti‐tumor immunity in a murine model for colorectal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Our research highlights how tumor sialylation affects tumor growth and reshapes the immune tumor microenvironment in colorectal cancer. We demonstrate for the first time that complete removal of sialic acids from colorectal tumor cells elicits a robust anti‐tumor immune response, but does not enhance anti‐PD‐L1 blockade efficacy.
Irene van der Haar Àvila   +11 more
wiley   +1 more source

Potential Spectral Tuning of the Tapetum Lucidum in a Broadly Distributed Ungulate

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The tapetum lucidum, a biological reflector system found in the eyes of many vertebrate species, enhances visual sensitivity in low light conditions by reflecting light back through the retina. The structure of the ungulate tapetum fibrosum is unique, and its reflectance varies temporally in reindeer (Rangifer tarandus).
Blaise A. Newman   +2 more
wiley   +1 more source

ATAC‐seq in Emerging Model Organisms: Challenges and Strategies

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Principle of ATAC‐seq (left), overview of arthropod species with published ATAC‐seq data (middle), summary of experimental design (right). ABSTRACT The Assay for Transposase‐Accessible Chromatin with sequencing (ATAC‐seq) is a versatile and widely utilized method for identifying potential regulatory regions, such as promoters and enhancers, within a ...
Duğçar Ebrar Erdoğan   +13 more
wiley   +1 more source

Simulations of the formation, evolution and clustering of galaxies and quasars

open access: yesNature, 2005
V. Springel   +16 more
semanticscholar   +1 more source

Are galaxies extending?

open access: yesPhysics Letters B, 2009
It is suggested that the recently observed size evolution of very massive compact galaxies in the early universe can be explained, if dark matter is in Bose Einstein condensate. In this model the size of the dark matter halos and galaxies depends on the correlation length of dark matter and, hence, on the the expansion of the universe.
openaire   +3 more sources

Diastereoselectivity in the Synthesis of m‐ and p‐Substituted 3‐Aryl‐2‐trichloromethyl‐1,3‐thiazolidin‐4‐one Sulfoxides With Oxone

open access: yesJournal of Heterocyclic Chemistry, EarlyView.
Highly selective oxidation of thiazolidin‐4‐ones to sulfoxides and sulfones with Oxone and KMnO4, respectively. ABSTRACT S‐Oxidation of 3‐Aryl‐2‐trichloromethyl‐1,3‐thiazolidin‐4‐ones with Oxone was investigated. For all compounds evaluated, selective oxidation to the sulfoxide versus the sulfone was realized using 3 equivalents of Oxone at room ...
Ahmed Y. Nuriye   +3 more
wiley   +1 more source

A Non‐Metaproteomics Researchers’ View on Metaproteomics in Microbiome Research

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Metaproteomics, an emerging field among the omic techniques, holds great promise for unraveling the function of microbiomes in host health and our environment. Metaproteomics can also be a valuable addition to multiomics studies of the microbiome, complementing genome‐resolved metagenomics, metatranscriptomics, and metabolomics.
Velma T. E. Aho   +5 more
wiley   +1 more source

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