Results 21 to 30 of about 1,330 (217)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Morphological Evolution of Galaxies [PDF]

open access: yesThe Astrophysical Journal, 1998
29 pages (AAS latex) + 7 figures (postscript) combined in one gzip-ed tar file. Submitted to The Astrophysical Journal (Dec 1996)
Hugo Martel   +4 more
openaire   +4 more sources

Mimicking Symmetry‐Breaking Einstein Ring by Optical Lens

open access: yesAdvanced Photonics Research, EarlyView.
This article uses an optical lens to emulate the gravitational lensing effect and observe the Einstein ring (ER) patterns. The symmetry‐breaking ER, i.e., Einstein cross, is observed utilizing a rotation‐symmetry‐breaking hemi‐ellipsoid lens. Deformed Einstein cross patterns induced by noncollinearly alignment of the light source–lens–observer are ...
Jun‐Liang Duan   +5 more
wiley   +1 more source

Scintillation Response of 0D Cs3Cu2I5 Thin Layers to Light‐ and Heavy‐Ion Irradiation

open access: yesAdvanced Photonics Research, EarlyView.
Driven by increasing interest in uncovering the remarkable photoluminescence quantum yield of Cs3Cu2I5, polycrystalline thin layers are synthesized to investigate its radioluminescence response to energetic ions. Its spectroscopic capability is assessed in a wide range of ion mass and internal excitation processes are explored.
Mátyás Hunyadi   +6 more
wiley   +1 more source

Galaxy Evolution in Clusters [PDF]

open access: yes, 2019
In this thesis, we aim to further elucidate the phenomenon of galaxy evolution in the environment of galaxy clusters using the methodology of numerical simulations. For that, we have developed hydrodynamic models in which idealized gas-rich galaxies move within the ICM of idealized galaxy clusters, allowing us to probe in a detailed and controlled ...
openaire   +2 more sources

The evolution of galaxy clustering [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1997
This paper investigates whether nonlinear gravitational instability can account for the clustering of galaxies on large and small scales, and for the evolution of clustering with epoch. No CDM-like spectrum is consistent with the shape of the observed nonlinear spectrum. Unbiased low-density models greatly overpredict the small-scale correlations; high-
openaire   +3 more sources

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu   +16 more
wiley   +1 more source

Cosmological evolution of galaxies [PDF]

open access: yes, 2013
I review the subject of the cosmological evolution of galaxies, including different aspects of growth in disk galaxies, by focussing on the angular momentum problem, mergers, and their by-products. I discuss the alternative to merger-driven growth -- cold accretion and related issues.
openaire   +3 more sources

Evolution of galaxy habitability [PDF]

open access: yesAstronomy & Astrophysics, 2016
We combine a semi-analytic model of galaxy evolution with constraints on circumstellar habitable zones and the distribution of terrestrial planets to probe the suitability of galaxies of different mass and type to host habitable planets, and how it evolves with time.
Sungwook E. Hong, Raphael Gobat
openaire   +4 more sources

Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa

open access: yesAdvanced Science, EarlyView.
Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang   +13 more
wiley   +1 more source

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